
1989 No. 2233
CONSUMER PROTECTION
The Cosmetic Products (Safety) Regulations 1989
Made 29th November 1989
Laid before Parliament 6th December 1989
Coming into force
(except as provided in regulation 1) 1st January 1990

Whereas the Secretary of State has, in accordance with section 11(5) of the Consumer Protection Act 1987, consulted such organisations as appear to him to be representative of interests substantially affected by these Regulations, such other persons as he considers appropriate and the Health and Safety Commission:
And whereas the Secretary of State is a Minister designated for the purposes of section 2 of the European Communities Act 1972 in relation to measures for safety and consumer protection as respects cosmetic products and any provisions concerning the composition, labelling, marketing, classification or description of cosmetic products and in relation to indication of origin on imported goods:

Now, therefore, the Secretary of State in exercise of powers conferred on him by sections 11, 28 and 30 of the said Act of 1987 and by section 2 of the said Act of 1972 and of all other powers enabling him in that behalf hereby makes the following Regulations:–
Citation, commencement and revocation
1 

(1) These Regulations may be cited as the Cosmetic Products (Safety) Regulations 1989 and except as provided by paragraphs (2) to (5) below shall come into force on 1st January 1990.
(2) Regulation 4(2) and Schedule 1, in so far as they relate only to entry numbers 37, 38, 47 (cross-referenced in column 3 with entry number 496) and 87 and to entry numbers 247, 558 and 680 (cross-referenced in column 3 with entry numbers 351, 454 and 132 respectively) in that Schedule, regulation 4(3) and Part I of Schedule 2, in so far as they relate only to entry number 52 in that Part, and regulation 4(5) and Part I of Schedule 4, in so far as they relate only to entry number 40 and the deletion of entry number 6 in that Part, shall come into force–
(a) on 1st January 1990 in relation to the supply of cosmetic products by the manufacturer in or importer into the United Kingdom or, in the case of cosmetic products manufactured or imported into the United Kingdom on behalf of another person, by that other person, except where the cosmetic products are supplied by retail in which case they shall come into force on 1st January 1991; and
(b) in all other cases, on 1st January 1991.
(3) Regulation 4(3) and Schedule 2, in so far as they relate only to entry numbers 53 and 54 in Part 1 of Schedule 2, regulation 4(4)(a)(i) and Part I of Schedule 3, in so far as they relate to the deletion of colouring agent 13065, and regulation 4(5) and Part II of Schedule 4, in so far as they relate to the deletion of entry numbers 7 to 10, 14, 18, 22 and 24 in that Part, shall come into force–
(a) on 1st January 1990 in relation to the supply of cosmetic products by the manufacturer in or importer into the United Kingdom or, in the case of cosmetic products manufactured or imported into the United Kingdom on behalf of another person, by that other person, except where the cosmetic products are supplied by retail in which case they shall come into force on 1st January 1992; and
(b) in all other cases, on 1st January 1992.
(4) Regulation 4(3) and Part II of Schedule 2, in so far as they relate only to entry number 1 in that Part, regulation 4(4) and Part II of Schedule 3, in so far as they relate only to the deletion of entry numbers 15800, 19120, 20470, 21115, 42170, 45190, 47000, 73905 and 75660 and the requirement in column 4 relating to entry number 42535 in that Part, regulation 4(5) and Part I of Schedule 4, in so far as they relate only to the requirement in column 4 relating to entry number 39 in that Part, and Part II of Schedule 4, in so far as they relate only to entry number 26 and the deletion of entry numbers 1, 3, 5, 19 and 25 in that Part, and regulation 4(6)(a)(ii) and Part II of Schedule 5 shall come into force–
(a) on 1st January 1991 in relation to the supply of cosmetic products by the manufacturer in or importer into the United Kingdom or, in the case of cosmetic products manufactured or imported into the United Kingdom on behalf of another person, by that other person, except where the cosmetic products are supplied by retail in which case they shall come into force on 1st January 1993; and
(b) in all other cases, on 1st January 1993.
(5) Regulation 6 shall come into force–
(a) on 1st January 1992 in relation to the supply of cosmetic products by the manufacturer in or importer into the United Kingdom or, in the case of cosmetic products manufactured or imported into the United Kingdom on behalf of another person, by that other person, except where the cosmetic products are supplied by retail in which case it shall come into force on 1st January 1994; and
(b) in all other cases on 1st January 1994.
(6) Subject to paragraph (7) below, the Regulations specified in Schedule 7 are hereby revoked:
(7) The notes in Schedules 3 and 4 shall apply.
Interpretation
2 

(1) In these Regulations–
 “the Directive” means Council Directive No.76/768/EEC as amended by Council Directive No. 82/368/EEC, Commission Directive No. 82/147/EEC, Commission Directive No. 83/191/EEC, Commission Directive No. 83/341/EEC, Council Directive No. 83/574/EEC, Commission Directive No. 83/496/EEC, Commission Directive No. 84/415/EEC, Commission Directive No. 85/391/EEC, Commission Directive No. 86/179/EEC, Commission Directive No. 86/199/EEC, Commission Directive No. 87/137/EEC, Commission Directive No. 88/233/EEC, Council Directive No. 88/667/EEC and Commission Directive No. 89/174/EEC;
 “cosmetic product” means any substance or preparation intended to be applied to any part of the external surfaces of the human body (that is to say, the epidermis, hair system, nails, lips and external genital organs) or to the teeth or buccal mucosa wholly or mainly for the purpose of cleaning, perfuming or protecting them or keeping them in good condition or changing their appearance or combating body odour or perspiration except where such cleaning, perfuming, protecting, keeping, changing or combating is wholly for the purpose of treating or preventing disease;
 “cosmetic product intended to come into contact with the mucous membranes” means a cosmetic product intended to be applied in the vicinity of the eyes, on the lips, in the oral cavity or to the external genital organs, and does not include any cosmetic product which is intended to come into only brief contact with the skin;
 “market research experiment” means any activities conducted for the purpose of ascertaining the opinion of persons of–
(a) any cosmetic product; or
(b) anything in, on or with which the cosmetic product is supplied; or
(c) the appearance or any other characteristic of the cosmetic product or any such thing; or
(d) the name or description under which the cosmetic product is supplied.
 A cosmetic product is not the subject of a market research experiment unless–
(a) any person to whom a cosmetic product is supplied in the course of the experiment is informed, at or before the time at which it is supplied to him, that it is supplied for the purpose of a market research experiment and
(b) no consideration in money or money’s worth is given by such a person for the cosmetic product or any other cosmetic product supplied to him for comparison.
 “preservative” means a substance which is added to a cosmetic product for the primary purpose of inhibiting the development of micro-organisms in that product;
 “supply” includes offering to supply, agreeing to supply, exposing for supply and possessing for supply, and cognate expressions shall be construed accordingly; and
 “UV filter” means a substance which is added to a sunscreen cosmetic product for the primary purpose of filtering ultra violet rays for the purpose of protecting the epidermis of the user from harmful effects of such ultra violet rays.
(2) References in these Regulations to a numbered regulation or Schedule are references to the regulation or Schedule so numbered in these Regulations.
General Requirements
3 

(1) Subject to paragraph (2) below, a cosmetic product shall not be liable to cause damage to human health when it is applied under normal conditions of use.
(2) For the purposes of regulation 8, paragraph (1) above shall apply only to the supply by the manufacturer in or importer into the United Kingdom or, in the case of cosmetic products manufactured or imported into the United Kingdom on behalf of another person, by that other person.
Particular requirements
4 

(1) The following provisions of this regulation are without prejudice to regulation 3 and are subject to regulation 5.
(2) A cosmetic product shall not contain any substance listed in column 2 of Schedule 1:Provided that no account shall be taken of any such substance which is present only as a trace which could not reasonably have been removed during or after manufacture.
(3) A cosmetic product shall not contain any substance listed in column 2 of Schedule 2 unless the requirements in columns 3, 4, 5 and (in the case of Part II) 7 of that Schedule in relation to that substance are satisfied.
(4) A cosmetic product shall not contain–
(a) any colouring agent listed in columns 1 and 2 of Schedule 3 with the exception of cosmetic products containing colouring agents intended solely to colour hair unless–
(i) the requirements in columns 3 and 4 of Part I of that Schedule in relation to that colouring agent are satisfied; or
(ii) the requirements in columns 3 and 4 of Part II of that Schedule in relation to that colouring agent are satisfied and the cosmetic product in question was supplied on or before the date specified in column 5 of that Part;
(b) any colouring agent which is not listed in that Schedule with the exception of cosmetic products containing colouring agents intended solely to colour hair;
(5) A cosmetic product shall not contain–
(a) any preservative listed in column 2 of Schedule 4 unless–
(i) the requirements in columns 3, 4 and 5 of Part I of that Schedule in relation to that preservative are satisfied; or
(ii) the requirements in columns 3, 4 and 5 of Part II of that Schedule in relation to that preservative are satisfied and the preservative in question is supplied on or before the date specified in column 7 of that Part;
(b) any preservative which is not listed in that Schedule;
(c) any preservative listed in column 2 of Part II of Schedule 4 after the date specified in column 7 of that Part.
(6) A cosmetic product shall not contain–
(a) any UV filter listed in column 2 of Schedule 5 unless–
(i) the requirements in columns 3 and 4 of Part I of that Schedule in relation to that UV filter are satisfied; or
(ii) the requirements in columns 3 and 4 of Part II of that Schedule in relation to that UV filter are satisfied and the UV filter in question is supplied on or before the date specified in column 6 of that Part;
(b) any UV filter which is not listed in that Schedule.
5 

(1) The Secretary of State may authorise the use in a cosmetic product of a particular substance, not being a substance listed in Schedule 1 or 2.
(2) In giving an authorisation the Secretary of State may impose conditions relating to the use of a particular substance in a cosmetic product. The conditions may relate to any matter which the Secretary of State considers appropriate including–
(a) the purpose of the substance;
(b) the type of cosmetic product;
(c) the maximum concentration of the substance in any cosmetic product; and
(d) information and marking requirements.
(3) The Secretary of State may on reasonable notice vary or revoke any authorisation given under paragraph (1) above.
(4) On giving, varying or revoking an authorisation, the Secretary of State shall arrange for the authorisation, variation or revocation, as the case may be, to be published in such manner as he considers appropriate for bringing it to the attention of persons who, in his opinion, would be likely to have an interest in it.
(5) No person shall be convicted of an offence under section 12 of the Consumer Protection Act 1987 by reason of a cosmetic product’s containing a particular substance provided that at the time when but for this regulation an offence would have been committed–
(a) the use of that particular substance in that cosmetic product was duly authorised; and
(b) all of the conditions imposed by the authorisation were complied with.
Marking
6 

(1) Subject to the following provisions of this regulation, the container and the outer packaging (if any) in which a cosmetic product is supplied or delivered pursuant to any supply, or a label affixed to the product, the container and the outer packaging, shall bear the following particulars:–
(a) the name or trade name and the address or registered office of the manufacturer of the product or of a supplier thereof, being a manufacturer or supplier established within a member State of the European Economic Community;
(b) in the case of a cosmetic product likely within 30 months from the manufacture thereof to cease either to comply with the requirements of regulation 3 or to fulfil the purpose for which it was intended, the words “Best before ” immediately followed by
(i) the earliest date on which it is likely to so cease; or
(ii) an indication of where that date appears on the labelling
and any particular precautions to be observed to ensure that the product does not so cease before that date.
(c) in the case of a cosmetic product containing a substance listed in column 2 of Schedule 2, the information specified in column 6 of that Schedule in relation to that substance;
(d) in the case of a cosmetic product containing a preservative listed in column 2 of Schedule 4, the information specified in column 6 of that Schedule in relation to that preservative;
(e) in the case of a cosmetic product containing a UV filter listed in column 2 of Schedule 5, the information specified in column 5 of that Schedule in relation to that UV filter;
(f) any particular precautions to be observed in use (not being precautions included in the information referred to in sub-paragraphs (b), (c), (d) and (e) above);
(g) a means of identifying the batch in which the product was manufactured (or, if the product was not manufactured in a batch, a reference from which the date and place of manufacture can be identified):
Provided that the requirements specified in sub-paragraphs (b) and (g) above need not be complied with in relation to a cosmetic product which is the subject of a market research experiment.
(2) The particulars referred to in sub-paragraphs (a) to (g) of paragraph (1) above shall be in lettering which is visible, indelible and easily legible.
(3) The particulars referred to in sub-paragraph (a) of paragraph (1) above may be abbreviated if such abbreviation does not prevent the person concerned from being identified.
(4) The date referred to in sub-paragraph (b) of paragraph (1) above shall include the month and the year, and the month shall precede the year.
(5) The particulars referred to in sub-paragraphs (b) to (f ) of paragraph (1) above shall be in the English language; but this shall not prohibit the additional use of other languages.
(6) The particulars referred to in sub-paragraphs (c) to (f ) of paragraph (1) above and any special precautionary information on cosmetic products for professional use, in particular, in hairdressing shall appear on the container or on a label attached thereto: provided that where–
(a) it is impracticable by reason of the size or shape of the container for the said particulars so to appear, or
(b) two or more products are supplied together as a single item, each product being in a separate container and the containers being enclosed together in outer packaging which bears clear and conspicuous instructions to the effect that the product must be mixed together in specified proportions before use,
the said particulars shall appear on an enclosed leaflet and an indication shall appear on both the container and the outer packaging (if any) or on a label if attached thereto referring the consumer to the information in the leaflet.
(7) Where it is impracticable, for reasons of size, for the particulars referred to in sub-paragraph (g) of paragraph (1) above to appear on the container and outer packaging, the said particulars shall appear on the packaging in which the product is exposed for supply.
(8) In the case of a supply of soap which is not in a container, either the soap itself or the packaging in which it is exposed for supply or the container in which it was last contained before the supply shall bear the particulars referred to in sub-paragraphs (a) and (g) of paragraph (1) above, and in so far as any of the particulars referred to in sub-paragraphs (b) to (f) of paragraph (1) above are required they shall appear on a leaflet which shall be delivered to the buyer with the soap; and where either of the particulars referred to in sub-paragraphs (a) and (g) of paragraph (1) above appears on the soap itself the requirement of indelibility shall apply only until it has been put into use.
Enforcement
7 

(1) No proceedings for an offence under section 12 of the Consumer Protection Act 1987 in respect of a contravention of regulation 8 by reason of the requirements of regulation 3 being not satisfied shall be brought in England or Wales except by or with the consent of the Secretary of State or the Director of Public Prosecutions and in Northern Ireland except by or with the consent of the Secretary of State or the Director of Public Prosecutions for Northern Ireland.
(2) Regulations 3, 4 and 6 do not apply in any case in which the cosmetic product is supplied for the purposes of exporting that product to any country which is not a member State of the European Economic Community.
(3) Regulation 6(5) does not apply in any case in which the person supplying the cosmetic product reasonably believes that it will not be used in the United Kingdom.
8 
Subject to regulations 5 and 7(2) and (3), no person shall supply any cosmetic product in respect of which any of the requirements of regulation 3, 4 or 6 is not satisfied.
9 
Any test of goods purchased under section 28, or seized under section 29, of the Consumer Protection Act 1987 (which relates to enforcement) by or on behalf of an enforcement authority for the purpose of ascertaining whether the provisions of these Regulations have been contravened shall in all cases be carried out in accordance with the provisions of paragraphs 2 to 5 of Schedule 6 and any test for which a method is specified in paragraph 6 of that Schedule shall be carried out in accordance with that method.
Eric Forth
Parliamentary Under-Secretary of State,
Department of Trade and Industry
29th November 1989
SCHEDULE 1
LIST OF SUBSTANCES WHICH COSMETIC PRODUCTS MUST NOT CONTAIN
Regulation 4(2)

The alphabetical list set out in column 2 of this Schedule contains one or more of the names of each of the substances referred to in regulation 4(2); in certain cases a name is given of a group of substances, the names of particular examples of which are also given, and in such a case all substances comprised in the group are included, whether or not more specifically named.
The numbers given in columns 1, 3 and 4 are for information only. Those in column 3 are cross-references to other names listed for the same substances (except that where a name is that of a group of substances, the cross-references are to particular examples of that group, and any cross-reference in parenthesis is to the name of a group of substances within which the particular substance falls). Those in column 4 are cross-references to Annex II of the Directive, from which this Schedule is derived.

(1) (2) (3) (4)
Number in this Schedule Name of substance Cross-reference to this Schedule Cross-reference to Annex II of the Directive
1 Acenocoumarol (INN) 3 254
2 3-(α-Acetonylbenzyl)-4-hydroxycoumarin and its salts 372, 704 203
3 3-(α-Acetonyl-p-nitrobenzyl)-4-hydroxycoumarin 1 254
4 2-(or β-)Acetoxyethyltrimethylammonium hydroxide and its salts 6 2
5 2-Acetylamino-5-chlorobenzoxazole 151 1
6 Acetylcholine and its salts 4 2
7 Acetylene chlorides 227, 702 126
8 Acetylenic alcohols, their esters, ethers and salts 17 16
9 Acetylethyltetramethyltetralin (AETT) 317 362
10 β-(7α-Acetylthio-17β-hydroxy-3-oxoandrost-4-en-17α-yl)propionic acid lactone 599 4
11 Aconitine and its salts — 12
12 Aconitum napellus L.(leaves, roots and galenical preparations) — 11
13 Adonis vernalis L. and its preparations — 13
14 Adrenaline 249, 294 14
15 Alkali pentacyanonitrosylferrate (2-) 563–4, 594–5 255
16 O-Alkyldithiocarbonic acids, salts of 705 336
17 Alkyne alcohols, their esters, ethers and salts 8 16
18 Alloclamide (INN) and its salts 22 19
19 Allyl isothiocyanate — 18
20 2-(4-Allyl-2-methoxyphenoxy)—N,N-diethylacetamide and its salts — 224
21 N-Allylnormorphine, its salts and ethers 460 20
22 2-Allyloxy-4-chloro—N-[2'-(diethylamino)ethyl]benzamide and its salts 18 19
23 Alypine and its salts 45, 103 143
24 Ambenomium chloride (INN) (492) 132
25 4-(orp-)Aminobenzoic acid esters except glycerol 1-(4-aminobenzoate) when provisionally permitted for use as a UV filter in accordance with the requirements specified in item 4 of Part II of Schedule 5 — 167
26 2-Amino-1,2-bis(4-methoxyphenyl) ethanol and its salts — 29
27 3-Amino-4-butoxybenzoic acid 2-diethylaminoethyl ester and its salts 95, 234 23
28 Aminocaproic acid (INN) and its salts 32 7
29 2-Amino-5-chlorobenzoxazole 710 24
30 4-Amino—N-(2'-diethylaminoethyl) benzamide, its salts and derivatives 566 23
31 Aminoheptane, its isomers and salts 695 27
32 6-Aminohexanoic acid and its salts 28 7
33 α-(Aminomethyl)-3,4-dihydroxybenzyl alcoholand its salts 483, 484 257
34 4-Amino—N10-methylfolic acid 425 6
35 2-Amino-6-methylheptane and its salts 390, 489 28
36 2-Amino-4-methylhexane and its salts 267, 442 30
37 2-Amino-4-nitrophenol — 383
38 2-Amino-5-nitrophenol — 384
39 4-(orp-)Aminosalicylic acid and its salts — 31
40 Aminotoluenes, their isomers, salts and halogenated and sulphonated derivatives 662 32
41 Aminoxylenes, their isomers, salts and halogenated and sulphonated derivatives 707 33
42 Amitriptyline (INN) and its salts 263 146
43 Ammi majus and its galenical preparations — 35
44 Amphetamine (INN), its salts and derivatives and salts of those derivatives (625) 21
45 Amydricaine and its salts 23, 103 143
46 Amylene chloride 228 36
47 Amyl 4-dimethylaminobenzoate, mixed isomers (Padimate A (INN)) 496 381
48 Amyl nitrites — 247
49 Amylobarbitone and its salts (68) 220
50 Amylocaine and its salts 261 50
51 Anamirta cocculus L.(fruit) — 106
52 Substances with androgenic effect — 37
53 Aniline, its salts and halogenated and sulphonated derivatives — 22
54 Anthracene oil — 38
55 Antibiotics (except tyrothricin) — 39
56 Antimony and its compounds — 40
57 Apocynum cannabinum L. and its preparations — 41
58 Apomorphine and its salts 641 42
59 Apronalide 393 216
60 Arecoline 451 238
61 Aristolochic acid and its salts — 365
62 Arsenic and its compounds — 43
63 Atropa belladonna L. and its compounds — 44
64 Atropine, its salts and derivatives — 45
65 Azacyclonol (INN) and its salts 285 286
66 Azamethonium bromide (INN) 443 121
67 Barbitone and its salts (68) 220
68 Barbiturates various 220
69 Barium salts (except barium sulphate, barium sulphide under the condition laid down in Part I of Schedule 2, for alkaline earth sulphides and lakes, salts and pigments prepared from those colouring agents identified in Column 1 of Schedule 3 by “*” immediately after the name or colour index number) — 46
70 Bemegride (INN) and its salts 311, 312 183
71 Benactyzine (INN) 235 157
72 Bendrofluazide and its derivatives 73, 86 53
73 Bendroflumethiazide (INN) and its derivatives 72, 86 53
74 Benzamine and its salts 688 51
75 Benzatropine (INN) and its salts 281 158
76 Benzazepines, their salts and derivatives 85 49
77 Benzene — 47
78 2-Benzhydryloxyethyldimethylamine and its salts 276 339
79 Benzidine 221 26
80 Benzilonium bromide (INN) 90 60
81 2-Benziloyloxymethyl-1,1-dimethylpyrrolidinium methylsulphate 561 239
82 Benzimidazolone 83, 244 48
83 Benzimidazol-2(3H)-one 82, 244 48
84 Benzoates of 4-hydroxy-3-methoxycinnamyl alcohol (except natural content of essences) 191 357
85 Benzodiazepines, their salts and derivatives 76 49
86 Benzothiadiazine and its derivatives 72, 73 53
87 Benzoyl peroxide — 382
88 3-(N-Benzylhydrazinocarbonyl)-5-methylisoxazole 387 52
89 Benzylideneacetone 527 356
90 3-Benzyloxy-1,1-diethylpyrrolidine hydrobromide 80 60
91 4-Benzyloxyphenol (366, 456) 178
92 2-[Benzyl—N-(2-pyridyl)amino]-ethyldimethylamine 581, 692 347
93 Beryllium and its compounds — 54
94 Betamethasone (INN) (337) 300
95 Betoxycaine (INN) and its salts 27, 95, 234 23
96 BHC (ISO) (gamma-BHC) 346, 348, 401 195
97 Bietamiverine (INN) 238 287
98 1,6-Bis(2-chloroethylamino)-1,6-dideoxymannitol and its salts 409 89
99 2-[Bis(2-chloroethyl)amino]-1-oxa-3-aza-2-phosphacyclohexane 2-oxide and its salts 102, 211 88
100 N,N-Bis(2-chloroethyl)methylamine and its salts 148, 458 87
101 N,N-Bis(2-chloroethyl)methylamine N-oxide and its salts 459 86
102 N,N-Bis(2-chloroethyl)—N',O-propylenephosphoramide anhydride and its salts 99, 211 88
103 1,1-Bis(dimethylaminomethyl)propyl benzoate and its salts 23, 45 143
104 2,2-Bis(hydroxymethyl)butan-1-ol trinitrate 572 206
105 2,6-Bis(β-hydroxyphenethyl)-1-methylpiperidine and its salts 403 219
106 Bithionol (INN) 651 352
107 Bretylium tosilate (INN) (or tosylate) 110 56
108 Bromine, elemental — 55
109 Bromisoval (INN) 113 58
110 p-Bromobenzylethyldimethylammoniump-toluenesulphonate 107 56
111 Bromodiethylacetylurea 112, 139 57
112 α-Bromo-α-ethylbutyrylurea 111, 139 57
113 Bromoisovalerylurea 109 58
114 1—p-bromophenyl-1-(2-pyridyl)-3-dimethylaminopropane and its salts 115 59
115 Brompheniramine (INN) and its salts 114 59
116 Brucine — 62
117 Butanilicaine (INN) and its salts 438 90
118 Butobarbitone and its salts (68) 220
119 Butopiprine (INN) and its salts 121 288
120 2-Butoxy—N-(2-diethylaminoethyl) cinchoninamide and its salts 178 129
121 2-Butoxyethyl α-phenyl-α-(N-piperidino)acetate and its salts 119 288
122 1-Butyl-3-(N-crotonoylsulphanilyl) urea — 108
123 4-Butyl-1,2-diphenylpyrazolidine-3,5-dione 526 67
124 4-Butyl-1-phenylpyrazolidine-3,5-dione 455 64
125 1-Butyl-3-(p-methylbenzenesulphonyl) urea 661 65
126 1-Butyl-3-sulphanilylurea 140 66
127 4-Butylthiobenzohydryl dimethylaminoethyl sulphide 133 140
128 Cadmium and its compounds — 68
129 Calabar bean 547 281
130 Cantharides,Cantharis vesicatoria 597 69
131 Cantharidin 354 70
132 Captan (ISO) 680 370
133 Captodiame (INN) 127 140
134 Caramiphen (INN) and its salts 530 169
135 N-(3-Carbamoyl-3,3-diphenylpropyl)—N,N-diisopropylmethylammonium salts 392 156
136 Carbazole, nitroderivatives of 476 72
137 Carbon disulphide — 73
138 Carbon tetrachloride 637 315
139 Carbromal (INN) 111, 112 57
140 Carbutamide (INN) 126 66
141 Carisoprodol (INN) 449 235
142 Catalase — 74
143 Cephaeline and its salts — 75
144 Chenopodium ambrosioides(essential oil) — 76
145 Cherry laurel water 577 291
146 Chloral hydrate 677 77
147 Chlorine — 78
148 Chlormethine (INN) and its salts 100,458 87
149 Chlormezanone (INN) 162 91
150 5-Chlorobenzoxazolinone 173 82
151 N-5-Chlorobenzoxazol-2-ylacetamide 5 1
152 2-Chloro-4-dimethylamino-6-methylpyrimidine 157, 196 83
153 2-Chloro-9-(α-dimethylamino-propylidine)thioxanthene (trans-form) and its salts 170 84
154 4-Chloro-1,3-disulphamoylbenzene 181 85
155 Chloroethane 305 96
156 Chloroform 679 366
157 2-Chloro-6-methylpyrimidin-4-yldimethylamine 152, 196 83
158 Chlorophacinone (ISO) 163 93
159 1-(p-Chloro-α-phenylbenzyl)-4-(2-hydroxyethoxyethyl)piperazine 376 240
160 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one 345 185
161 2-(4-Chlorophenyl)-3-methylbutane-2,3-diol 516 95
162 2-(4-Chlorophenyl-3-methyl-4-metathiazonone-1,1-dioxide 149 91
163 2-[2-(4-Chlorophenyl)-2-phenylacetyl]indan-1,3-dione 158 93
164 1-(4-Chlorophenyl)-1-phenyl-1-dimethylaminoethoxyethane 167 94
165 Chloropicrine — 325
166 3-(4-Chloro-3-sulphamoylphenyl)-3-hydroxyisoindolin-1-one 171, 172 262
167 Chlorphenoxamine (INN) 164 94
168 Chlorpromazine (INN) (521) 320
169 Chlorpropamide (INN) 573 79
170 Chlorprothixene (INN) and its salts 153 84
171 Chlortalidone (INN) 166, 172 262
172 Chlorthalidone 166, 171 262
173 Chlorzoxazone (INN) 150 82
174 Cholecalciferol (703) 335
175 Choline salts and their esters — 168
176 Chromium, chromic acid and salts of the acid — 97
177 Chrysoidine citrate hydrochloride 525 81
178 Cinchocaine (INN) and its salts 120 129
179 Cincophen (INN), its salts and derivatives and salts of those derivatives 539 8
180 Claviceps purpurea Tul., its alkaloids and galenical preparations 296 98
181 Clofenamide (INN) 154 85
182 Clofenotane (INN) 213, 676 123
183 Cobalt benzenesulphonate — 101
184 Cocculin 551 282
185 Colchicine, its salts and derivatives — 102
186 Colchicoside and its derivatives — 103
187 Colchicum autumnale L. and its galenical preparations — 104
188 Colouring agent CI 12140 — 378
189 Colouring agent CI 26105 — 379
190 Colouring agents CI 42555, 42555–1 and 42555–2 — 380
191 Coniferyl benzoate (except natural content of essences) 84 357
192 Coniine 574 290
193 Conium maculatum L. (fruit, powder, galenical preparations) — 99
194 Convallatoxin — 105
195 Coumetarol (INN) 427 225
196 Crimidine (ISO) 152, 157 83
197 Croton tiglium(oil) — 107
198 Curare and curarine — 109
199 Curarizants, synthetic — 110
200 Cyanides 363, 365 111
201 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylic acid ethyl ester hydrochloride 277 80
202 Cyclarbamate (INN) 210 122
203 Cyclizine (INN) and its salts 282 159
204 Cyclobarbitone and its salts (68) 220
205 Cyclocoumarol 245 234
206 2-α-Cyclohexylbenzyl(N,N,N',N'-tetraethyl)trimethylenediamine 517 112
207 2-Cyclohexyl-3,5-dimethylphenol and its salts 209 113
208 1-Cyclohexyl-3-(p-methylbenzenesulphonyl)urea 340 100
209 Cyclomenol (INN) and its salts 207 113
210 Cyclopentane-1,1-dimethanol dicarbanilate 202 122
211 Cyclophosphamide (INN) and its salts 99, 102 88
212 Datura stramonium L. and its galenical preparations 601 301
213 DDT (ISO) (p,p'-DDT) 182, 676 123
214 Deanol aceglumate (INN) 256 3
215 Decamethonium bromide (INN) 216 214
216 Decamethylenebis(trimethylammonium) salts 215 214
217 Dextromethorphan (INN) and its salts 430 226
218 Dextropropoxyphene (INN) 260 116
219 O,O'-Diacetyl-N-allyl—N-normorphine — 117
220 1,2-Diaminobenzene and its salts 533 363
221 p,p'-Diaminodiphenyl 79 26
222 1,4:3,6-Dianhydrosorbitol 2,5-dinitrate 395 148
223 5-(α, β-Dibromophenethyl)-5-methylhydantoin — 119
224 Dibromosalicylanilides 225, 416 351
225 Dibromsalan (INN) (224) 351
226 Dichloroethanes 306, 309 125
227 Dichloroethylenes 7, 702 126
228 2,3-Dichloro-2-methylbutane 46 36
229 Dichlorosalicylanilides — 349
230 Dicoumarin 231, 440 231
231 Dicoumarol (INN) 230, 440 231
232 2-(Diethylaminoethoxy)ethyl α-phenylpiperidine-1-acetate dimethiodide 560 137
233 1-[4-(β-Diethylaminoethoxy)phenyl]-1-(4-tolyl)-2-(4-chlorophenyl)-ethanol 691 92
234 2-Diethylaminoethyl 3-amino-4-butoxybenzoate and its salts 27, 95 23
235 2-Diethylaminoethyl benzilate and its salts 71 157
236 2-Diethylaminoethyl 4-ethoxybenzoate and its salts 383, 500 179
237 2-Diethylaminoethyl 3-hydroxy-4-phenylbenzoate and its salts — 128
238 2-Diethylaminoethyl α-phenyl-α-(N-piperidino)acetate 97 287
239 3-Diethylaminopropyl cinnamate — 130
240 Diethyl 4-nitrophenyl phosphate 498 170
241 O,O-DiethylO-4-nitrophenyl phosphorothioate 499 131
242 Difencloxazine (INN) 529 270
243 Digitaline and all heterosides ofDigitalis purpurea L. — 134
244 4,5-Dihydrobenzimidazol-4-one 82, 83 48
245 3,4-Dihydro-2-methoxy-2-methyl-4-phenyl-2H, 5H-pyrano [3,2—c]-[1]-benzopyran-5-one 205 234
246 Dihydrotachysterol (INN) — 342
247 2,2'-Dihydroxy-3,3',5,5'6,6'-hexachlorodiphenylmethane (hexachlorophene) 351 371
248 3,4-Dihydroxy-α-(isopropylaminomethyl)benzyl alcohol 391, 394 17
249 3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol 14, 294 14
250 4,4'-Dihydroxy-3,3'-(3-methylthiopropylidene)dicoumarin — 207
251 1-(3,4-Dihydroxyphenyl)-2-ethylaminopropan-1-ol 274 136
252 5,5'-Di-isopropyl-2,2'-dimethylbiphenyl-4,4'-diyl dihypoiodite 385 361
253 Dimethoxane 265 368
254 4-[β-(3,4-Dimethoxyphenyl)ethyl]-1-(2-chlorophenyl)piperazine and its salts 411 141
255 Dimethylamine — 142
256 2-DimethylaminoethylN-acetylglutamate 214 3
257 2-[α-(2-Dimethylaminoethoxy)-α-methylbenzyl]pyridine and its salts 290 176
258 2-Dimethylaminoethylp-butylaminobenzoate and its salts 634 63
259 2-[(2-Dimethylaminoethyl)-2-thienylamino]pyridine and its salts 421 144
260 (+)-4-Dimethylamino-3-methyl-1,2-diphenyl-2-propionyloxybutane 218 116
261 1-Dimethylaminomethyl-1-methylpropyl benzoate and its salts 50 50
262 2-Dimethylaminopropiophenone and its salts 418 145
263 3-(3-Dimethylaminopropylidene)-1,2:4,5-dibenzocyclohepta-1,4-diene and its salts 42 146
264 N,N-Dimethyldiguanide and its salts 420 147
265 2,6-Dimethyl-1,3-dioxan-4-yl acetate (Dimethoxane) 253 368
266 Dimethylformamide — 355
267 1,3-Dimethylpentylamine and its salts 36, 442 30
268 1,2-Dimethyl-4-phenyl-4-carbmethoxyhexamethyleneimine and its salts 422 174
269 1,3-Dimethyl-4-phenyl-4-carboxyethylhexamethyleneimine and its salts 419 171
270 Dimethyl sulphoxide (INN) — 338
271 Dimevamide (INN) and its salts 278 153
272 Dinitrophenol isomers — 151
273 Dioxane — 343
274 Dioxethedrin (INN) and its salts 251 136
275 2,5-Dioxo-3,3-diethyl-5-methylpiperidine and its salts 452 133
276 Diphenhydramine (INN) and its salts 78 339
277 Diphenoxylate hydrochloride (INNM) 201 80
278 2,2-Diphenyl-4-dimethylamino-valeramide and its salts 271 153
279 5,5-Diphenyl-4-imidazolidone — 160
280 4-Diphenylmethoxy-1-methylpiperidine and its salts 286 154
281 3-Diphenylmethoxytropane and its salts 75 158
282 1-Diphenylmethyl-4-methylpiperazine 203 159
283 1,2-Diphenyl-4-(2-phenylsulphinylethyl)pyrazolidine-3,5-dione 608 155
284 α,α-Diphenyl-2-piperidinemethanol 559 285
285 α,α-Diphenyl-4-piperidinemethanol 65 286
286 Diphenylpyraline (INN) and its salts 280 154
287 2,5-Dipropoxy-3,6-bis(ethyleneimino)-1,4-benzoquinone 382 152
288 4-Dipropylsulphamylbenzoic acid 565 161
289 Disulfiram (INN) 645, 656 162
290 Doxylamine (INN) and its salts 257 176
291 Emetine, its salts and derivatives — 163
292 Endrin (ISO) 349 196
293 Ephedrine and its salts — 164
294 Epinephrine (INN) 14, 249 14
295 Ergocalciferol (INN) (703) 335
296 Ergot, its alkaloids and galenical preparations 180 98
297 Eserine and its salts 548 166
298 Ethionamide (INN) 310 319
299 Ethoheptazine (INN) and its salts 446 173
300 Ethopropazine and its salts (521) 320
301 4-Ethoxyphenol (366, 456) 178
302 2-Ethylamino-5-phenyloxazolin-4-one 319 180
303 Ethyl bis(4-hydroxycoumarinyl)-acetate and salts of the acid 304 204
304 Ethyl bis(4-hydroxy-2-oxo-1-benzopyran-3-yl)acetate and salts of the acid 303 204
305 Ethyl chloride 155 96
306 Ethylene dichloride (226) 125
307 Ethylene oxide — 182
308 2-Ethyl-2,3-epoxyhexamide and its derivatives 493 165
309 Ethylidene chloride (226) 125
310 3-Ethylisothionicotinamide 298 319
311 β-Ethyl-β-methylglutarimide and its salts 70, 312 183
312 4-Ethyl-4-methylpiperidine-2,6-dione and its salts 70, 311 183
313 β-Ethyl-β-methylvaleramide 698 184
314 Ethylphenacemide (INN) 528 272
315 2-Ethyl-2-phenylglutarimide and its salts 316, 338 181
316 3-Ethyl-3-phenylpiperidine-2,6-dione and its salts 315, 338 181
317 3'-Ethyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'-acetonaphthone 9 362
318 Fenadiazole (INN) 374 208
319 Fenozolone (INN) 302 180
320 Fenyramidol (INN) 538, 541 274
321 Fluanisone (INN) 326 187
322 Fluoresone (INN) 325 189
323 4'-Fluoro-4-[4-hydroxy-4-(α,α,α-trifluoro—m-tolyl)piperidino]-butyrophenone 685 188
324 6-Fluoro-16-methyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione 497 186
325 p-Fluorophenylethylsulphone 322 189
326 1-(4-Fluorophenyl)-4-[4-(2-methoxyphenyl)-1-piperazinyl]-butan-1-one 321 187
327 5-Fluoropyrimidine-2,4-dione 328 190
328 Fluorouracil (INN) 327 190
329 Fluphenazine (INN) (521) 320
330 Furazolidone (INN) 479 252
331 Furfuryltrimethylammonium salts 334 192
332 Furo[3,2—g]chromen-7-one and its alkyl-substituted derivatives (except natural content of essences) 333, 434, 690 358
333 Furocoumarin and its alkyl-substituted derivatives (except natural content of essences) 332, 434, 690 358
334 Furtrethonium iodide (INN) 331 192
335 Galantamine (INN) — 193
336 Gallamine triethiodide (INN) 693 329
337 Glucocorticoids 94 300
338 Glutethimide (INN) and its salts 315, 316 181
339 Glycerol trinitrate 480, 571 253
340 Glycyclamide (INN) 208 100
341 Gold salts — 296
342 Guaifenesin (INN) 432 230
343 Guanethidine (INN) and its salts 344 259
344 N-(2-Guanidinoethyl)heptamethyleneimine and its salts 343 259
345 Haloperidol (INN) 160 185
346 HCH (ISO) (gamma-HCH) 96, 348, 401 195
347 HETP 353 316
348 1,2,3,4,5,6-Hexachlorocyclohexane 96, 346, 401 195
349 (1R, 4S, 5R, 8S)-1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalene 292 196
350 Hexachloroethane — 197
351 Hexachlorophene (INN) 247 371
352 (1R,4S,5R,8S)-1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene 388 198
353 Hexaethyl tetraphosphate 347 316
354 (1R,2S)-Hexahydro-1,2-dimethyl-3,6-epoxyphthalic anhydride 131 70
355 (3S,5aR,9bS)-3,3a,4,5,5a,9b-Hexahydro-3,5a,9-trimethylnaphtho-[1,2-b]furan-2,8-dione 587 217
356 Hexamethonium bromide (INN) (357) 124
357 N,N'-Hexamethylenebis(trimethylammonium) salts 356 124
358 Hexapropymate (INN) 575 115
359 Hydrastine, hydrastinine and their salts — 199
360 Hydrazides and their salts — 200
361 Hydrazine, its derivatives and their salts — 201
362 2-Hydrazino-octane and its salts 487 202
363 Hydrocyanic acid and its salts 200, 365 111
364 Hydrofluoric acid, its normal salts, complexes and hydrofluorides (except those listed in Part I of Schedule 2) — 191
365 Hydrogen cyanide and its salts 200, 363 111
366 Hydroquinone monobenzyl, monoethyl and monomethyl ethers 91, 301, 431, (456) 178
367 7-[2-Hydroxy-3-(2-hydroxyethyl—N-methylamino)propyl]theophylline 706 135
368 [4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid and its salts 686 5
369 3-[4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propionic acid and its salts 659 9
370 1-Hydroxymethyl-1-cyclohexylacetic acid, sodium salt 593 114
371 8-Hydroxy-5(or 6)-nitroquinoline and its salts 482 209
372 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-coumarin and its salts 2, 704 203
373 1-(4-Hydroxy-β-phenylethyl)-4-phenyl-4-carbethoxypiperidine and its salts 495 172
374 2-(4-Hydroxyphenyl-1,3,4-oxadiazole 318 208
375 1-Hydroxy-2,4,6-trinitrobenzene 550, 689 268
376 Hydroxyzine (INN) 159 240
377 Hyoscine, its salts and derivatives 590 295
378 Hyoscyamine, its salts and derivatives — 210
379 Hyoscyamus niger L(leaves, seeds powder and galenical preparations) — 211
380 2-Imino-5-phenyloxazolidin-4-one and its salts 502 212
381 Imperatorin 437 34
382 Inproquone (INN) 287 152
383 Intracaine and its salts 236, 500 179
384 Iodine — 213
385 Iodothymol 252 361
386 Ipecacuanha (Cephaelis ipecacuanha Brot. and related species) (roots, powder and galenical preparations) — 215
387 Isocarboxazid (INN) 88 52
388 Isodrin 352 198
389 Isometheptene (INN) and its salts 435 228
390 2-Isooctylamine and its salts 35, 489 28
391 Isoprenaline (INN) 248, 394 17
392 Isopropamide iodide (INN) 135 156
393 (2-Isopropylpent-4-enoyl)urea 59 216
394 Isoproterenol 248, 391 17
395 Isosorbide dinitrate (INN) 222 148
396 Juniperus sabina L. (leaves, essential oil and galenical preparations) — 294
397 Laurel oil 398 359
398 Laurus nobilis L. (oil from seeds) 397 359
399 Lead and its compounds (except lead acetate) — 289
400 Levophacetoperane and its salts 556 284
401 Lindane 96, 346, 348 195
402 Lobelia inflata L. and its galenical preparations — 218
403 Lobeline (INN) and its salts 105 219
404 LSD 406, 407 127
405 Lupinidine and its salts 598 299
406 Lysergic acid diethylamide and its salts 404, 407 127
407 Lysergide (INN) and its salts 404, 406 127
408 Malononitrile — 149
409 Mannomustine (INN) and its salts 98 89
410 Mecamylamine (INN) 644 229
411 Mefeclorazine (INN) and its salts 254 141
412 Mephenesin (INN) and its esters 664 322
413 Meprobamate (INN) 450 236
414 Mercury and its compounds (except those listed in Part III of Schedule 2 or in Part I of Schedule 4) — 221
415 Mescaline and its salts 687 222
416 Metabromsalan (INN) (224) 351
417 Metaldehyde 562 223
418 Metamfepramone (INN) and its salts 262 145
419 Metethoheptazine (INN) and its salts 269 171
420 Metformin (INN) and its salts 264 147
421 Methapyrilene (INN) and its salts 259 144
422 Metheptazine (INN) and its salts 268 174
423 Methocarbamol (INN) 433 205
424 Methohexitone and its salts (68) 220
425 Methotrexate (INN) 34 6
426 2-[4-Methoxybenzyl—N-(2-pyridyl)amino]ethyldimethylamine maleate 580 346
427 1-Methoxy-2,2-bis(4-hydroxy-3-coumarinyl)ethane 195 225
428 1-Methoxy-2,4-diaminobenzene (2,4-diaminoanisole-CI 76050) — 376
429 1-Methoxy-2,5 diaminobenzene (2,5-diaminoanisole) — 377
430 (+)-3-Methoxy—N-methylmorphinan and its salts 217 226
431 4-Methoxyphenol (366, 456) 178
432 3-(4-Methoxyphenoxy)propane-1,2-diol 342 230
433 3-(2-Methoxyphenoxy)propane-1,2-diol 1-carbamate 423 205
434 8-Methoxypsoralen (except natural content of essences) 332, 333, 690 358
435 6-Methylamino-2-methylhept-2-ene and its salts 389 228
436 2-Methyl-1,2-bis(3-pyridyl)-propan-1-one 453 292
437 9-(3-Methylbut-2-enyloxy)furo-[3,2—g]chromen-7-one 381 34
438 2-Methyl-6-chloroanilide of n-butylaminoacetic acid and its salts 117 90
439 1-Methyl-2,4-diaminobenzene and its salts 447 364
440 3,3-Methylenebis-(4-hydroxycoumarin) 230, 231 231
441 2-Methylheptylamine and its salts — 227
442 4-Methyl-2-hexylamine and its salts 36, 267 30
443 N,N'-[(Methylimino)diethylene]bis-(ethyldimethylammonium) salts 66 121
444 1-Methyl-2-mercaptoimidazole 650 233
445 Methylphenidate (INN) and its salts 535 175
446 1-Methyl-4-phenyl-4-carbethoxyhexamethyleneimine and its salts 299 173
447 4-Methyl—m-phenylenediamine and its salts 439 364
448 3-Methyl-2-phenylmorpholine, its derivatives and salts 519 232
449 2-Methyl-2-propyl-1-isopropylcarbamoyloxy-3-carbamoyloxypropane 141 235
450 2-Methyl-2-propylpropane-1,3-diol dicarbamate 413 236
451 N-Methyl-1,2,5,6-tetrahydro-3-nicotinic acid methyl ester 60 238
452 Methyprylon (INN) and its salts 275 133
453 Metyrapone (INN) 436 292
454 Minoxidil (INN), its salts and derivatives 558 372
455 Mofebutazone (INN) 124 64
456 Monobenzone (INN) 91, 301, (366) 431 178
457 Morpholine and its salts — 344
458 Mustine and its salts 100, 148 87
459 MustineN-oxide and its salts 101 86
460 Nalorphine (INN), its salts and ethers 21 20
461 Naphazoline (INN) and its salts 467 244
462 2-Naphthol 463 241
463 β-Naphthol 462 241
464 1-and 2-Naphthylamines and their salts 465 242
465 α-and β-Naphthylamines and their salts 464 242
466 3-(1-Naphthyl)-4-hydroxycoumarin — 243
467 2-(1-Naphthylmethyl)imidazoline and its salts 461 244
468 Narcotics, natural and synthetic: All substances listed in Tables I and II of the Single Convention on Narcotic Drugs 1961 (Treaty Series No. 34(1965), Cmnd. 2631) — 306
469 Narcotine and its salts 485 258
470 Neodymium and its salts — 309
471 Neostigmine and its salts — 245
472 Nicotine and its salts — 246
473 Nitrites, inorganic (except sodium nitrite) — 248
474 Nitrobenzene — 249
475 Nitrocresols and their alkali metal salts — 250
476 Nitroderivatives of carbazole 136 72
477 Nitrofurantoin (INN) 478 251
478 N-(5-Nitro-2-furfurylidene)-1-aminohydantoin 477 251
479 3-(5-Nitrofurfurylideneamino)-oxazolidin-2-one 330 252
480 Nitroglycerine 339, 571 253
481 Nitrostilbenes, their homologues and derivatives — 256
482 Nitroxoline (INN) and its salts 371 209
483 Noradrenaline and its salts 33, 484 257
484 Norepinephrine and its salts 33, 483 257
485 Noscapine (INN) and its salts 469 258
486 Nux vomica and its preparations 605 305
487 Octamoxin (INN) and its salts 362 202
488 Octamylamine (INN) and its salts 510 267
489 Octodrine (INN) and its salts 35, 390 28
490 Oestrogens — 260
491 Oleandrin — 261
492 [Oxalylbis(iminoethylene)]bis-[(o-chlorobenzyl)diethylammonium] salts 24 132
493 Oxanamide (INN) and its derivatives 308 165
494 2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo-[a]quinolizine and its salts 632 139
495 Oxpheneridine (INN) and its salts 373 172
496 Padimate A 47 381
497 Paramethasone (INN) 324 186
498 Paraoxon 240 170
499 Parathion (ISO) 241 131
500 Parethoxycaine (INN) and its salts 236, 383 179
501 Pelletierine and its salts 557 263
502 Pemoline (INN) and its salts 380 212
503 Pentachloroethane — 264
504 Pentaerythritol chloral 514 266
505 Pentaerythritol tetranitrate 506, 513 265
506 Pentaerythrityl tetranitrate (INN) 505, 513 265
507 Pentamethonium bromide (INN) 508 120
508 N,N'-Pentamethylenebis-(trimethylammonium) salts 507 120
509 Pentobarbitone and its salts 68 220
510 Pentylaminomethylheptane, its isomers and salts 488 267
511 Perchloroethylene 636 314
512 Perphenazine (INN) and its salts (521) 320
513 PETN 505, 506 265
514 Petrichloral (INN) 504 266
515 Phenacemide (INN) 524 269
516 Phenaglycodol (INN) 161 95
517 Phenetamine 206 112
518 Phenindone (INN) 534 271
519 Phenmetrazine (INN), its derivatives and salts 448 232
520 Phenobarbitone and its salts (68) 220
521 Phenothiazine (INN) and its compounds various 320
522 Phenprobamate (INN) 536 71
523 Phenprocoumon (INN) 537 273
524 N-Phenylacetylurea 515 269
525 4-Phenylazophenylene-1,3-diamine citrate hydrochloride 177 81
526 Phenylbutazone (INN) 123 67
527 4-Phenylbut-3-en-2-one 89 356
528 N-(2-Phenylbutyryl)urea 314 272
529 N-[2-(α-Phenyl—p-chlorobenzyl)-ethyl]morpholine 242 270
530 1-Phenylcyclopentanecarboxylic acid diethylaminoethyl ester and its salts 134 169
531 2-Phenylcyclopropylamine (trans-form) and its salts 665, 666 324
532 1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one 576 138
533 o-Phenylenediamine and its salts 220 363
534 2-Phenylindan-1,3-dione 518 271
535 α-Phenyl-2-piperidineacetic acid methyl ester and its salts 445 175
536 1-Phenylpropan-1-ol carbamate 522 71
537 3-(α-Phenylpropyl)-4-hydroxycoumarin 523 273
538 1-Phenyl-2-(2-pyridylamino)ethanol 320, 541 274
539 2-Phenylquinoline-4-carboxylic acid, its saltsand derivatives and salts of those derivatives 179 8
540 6-Phenyl-2,4,7-triaminopteridine and its salts 669 275
541 Phenyramidol 320, 538 274
542 Phosphides, metal 543 279
543 Phosphorus 542 279
544 4-Phosphoryloxy—N,N-dimethyl-tryptamine 578 278
545 3-Phthalimidopiperidine-2,6-dione and its salts 647 280
546 Phthalylsulphathiazole (INN) and its salts (622) 307
547 Physostigma venenosum Balf. 129 281
548 Physostigmine and its salts 297 166
549 Phytolacca Spp and their preparations — 374
550 Picric acid 375, 689 268
551 Picrotoxin 184 282
552 Pilocarpine and its salts — 283
553 Pilocarpus jaborandi Holmes and its galenical preparations — 311
554 Pipazetate (INN) and its salts 555 118
555 2-(2-Piperidinoethoxy)ethyl-10-thia-1,9-diazaanthracene-9-carboxylate and its salts 554 118
556 α-Piperidin-2-ylbenzyl acetate, laevorotatorythreo-form 400 284
557 β-(2-Piperidyl)propionaldehyde and its salts 501 263
558 6-(Piperidinyl)-2,4-pyrimidinediamine-3-oxide (Minoxidil) and its salts and derivatives 454 372
559 Pipradrol (INN) and its salts 284 285
560 Piprocurarium iodide (INN) 232 137
561 Poldine metilsulfate (INN) (or methylsulphate) 81 239
562 Polyacetaldehyde 417 223
563 Potassium nitroferricyanide 15, 564, 594–5 255
564 Potassium nitroprusside 15, 563, 594–5 255
565 Probenecid (INN) 288 161
566 Procainamide (INN), its salts and derivatives 30 25
567 Prochlorperazine (INN) and its salts (521) 320
568 Progestogens (except progesterone and ethisterone) — 194
569 Promazine (INN) and its salts (521) 320
570 Promethazine (INN) and its salts (521) 320
571 Propane-1,2,3-triyl trinitrate 339, 480 253
572 Propatylnitrate (INN) 104 206
573 1-Propyl-3-(4-chlorobenzene-sulphonyl)urea 169 79
574 2-Propylpiperidine 192 290
575 1-(2-Propynyl)cyclohexyl carbamate 358 115
576 Propyphenazone (INN) 532 138
577 Prunus laurocerasus L. 145 291
578 Psilocybine (INN) 544 278
579 Pyrethrum album L. and its galenical preparations — 345
580 Pyrianisamine maleate 426 346
581 Pyribenzamine 92, 692 347
582 Pyrithione sodium (INNM) — 369
583 Quinalbarbitone and its salts (68) 220
584 Radioactive substances (except substances which are radioactive naturally or by reason of contamination from the environment, which have not been enriched for manufacturing purposes, and of which the concentration complies with Council Directive No. 76/579/Euratom) — 293
585 Rauwolfia serpentina alkaloids and their salts 586 15
586 Reserpine (INN) and its salts (585) 15
587 α-Santonin 355 217
588 Safrole (except natural content of essences in cases where the concentration of such safrole in the cosmetic product does not exceed–
(a) in the case of oral hygiene or dental products other than toothpaste intended specifically for children, 50 ppm; or
(b) in the case of products other than oral hygiene or dental products, 100 ppm.) — 360
589 Schoenocaulon officinale Lind.(seeds and galenical preparations) — 332
590 Scopolamine, its salts and derivatives 377 295
591 Secbutobarbitone and its salts (68) 220
592 Selenium and its compounds except when permitted under the restrictions laid down in Part I of Schedule 2 — 297
593 Sodium hexacyclonate (INN) 370 114
594 Sodium nitroferricyanide 15, 563, 564, 595 255
595 Sodium nitroprusside 15, 563, 564,594 255
596 Solanum nigrum L. and its galenical preparations — 298
597 Spanish Fly 130 69
598 Sparteine (INN) and its salts 405 299
599 Spironolactone (INN) 10 4
600 Squill and its preparations 696 330
601 Stramonium and its preparations 212 301
602 Strophanthines and their aglucones and their respective derivatives — 302
603 Strophanthus species and their galenical preparations — 303
604 Strychnine and its salts — 304
605 Strychnos species and their galenical preparations 486 305
606 Succinonitrile — 150
607 Succinylsulphathiazole and its salts (622) 307
608 Sulfinpyrazone (INN) 283 155
609 Sulphacetamide and its salts (622) 307
610 Sulphadiazine and its salts (622) 307
611 Sulphadimethoxine and its salts (622) 307
612 Sulphadimidine and its salts (622) 307
613 Sulphafurazole and its salts (622) 307
614 Sulphaguanidine and its salts (622) 307
615 Sulphamethizole and its salts (622) 307
616 Sulphamethoxazole and its salts (622) 307
617 Sulphamethoxydiazine and its salts (622) 307
618 Sulphamethoxypyridazine and its salts (622) 307
619 Sulphanilamide and its salts (622) 307
620 Sulphapyridine and its salts (622) 307
621 Sulphathiazole and its salts (622) 307
622 Sulphonamides (sulphanilamide and its derivatives obtained by substitution of one or more H-atoms of the —NH2 groups) and their salts various 307
623 Sulthiame 624, 643 308
624 Sultiame (INN) 623, 643 308
625 Sympathomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and are referred to in resolution AP (69) 2 of the Council of Europe 44 21
626 Tefazoline (INN) and its salts 642 237
627 Tellurium and its compounds — 312
628 TEPP (ISO) 640 276
629 2-(4—tert-Butyl-2,6-dimethylbenzyl)-imidazoline and its salts 708 313
630 4—tert-Butylphenol — 340
631 4—tert-butylpyrocatechol — 341
632 Tetrabenazine (INN) and its salts 494 139
633 Tetrabromosalicylanilides — 350
634 Tetracaine (INN) and its salts 258 63
635 2,3,7,8-Tetrachlorodibenzo—p-dioxin — 367
636 Tetrachloroethylene 511 314
637 Tetrachloromethane 138 315
638 Tetrachlorosalicylanilides — 348
639 Tetraethylammonium bromide 646 61
640 Tetraethyl pyrophosphate 628 276
641 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-dihydric alcohol and its salts 58 42
642 2-(5,6,7,8-Tetrahydro-1-methyl-2-naphthyl)-2-imidazoline and its salts 626 237
643 4-(Tetrahydro-2H-1,2-thiazin-2-yl)-benzenesulphonamideS,S-dioxide 623, 624 308
644 N,2,3,3-Tetramethyl-2-norcamphanamine 410 229
645 Tetramethylthiuam disulphide 289, 656 162
646 Tetrylammonium bromide (INN) 639 61
647 Thalidomide (INN) and its salts 545 280
648 Thallium and its compounds — 317
649 Thevetia neriifolia Juss., glycoside extract — 318
650 Thiamazole (INN) 444 233
651 2,2'-Thiobis(4,6-dichlorophenol) 106 352
652 Thiopentone and its salts (68) 220
653 Thioridazine (INN) and its salts (521) 320
654 Thiotepa (INN) 670, 683 310
655 Thiourea and its derivatives (except the one listed in Part I of Schedule 2) — 321
656 Thiram (ISO) 289, 645 162
657 Thiuram disulphides — 354
658 Thiuram monosulphides — 353
659 Thyropropic acid (INN) and its salts 369 9
660 Tolboxane (INN) 663 177
661 Tolbutamide (INN) 125 65
662 Toluidines, their isomers, salts and halogenated and sulphonated derivatives 40 32
663 p-Tolylboric acid ester of 2-methyl-2-propylpropane-1,3-diol 660 177
664 3—o-Tolyloxypropane-1,2-diol 412 322
665 trans-2-Phenylcyclopropylamine and its salts 531, 666 324
666 Tranylcypromine (INN) and its salts 531, 665 324
667 Tretamine (INN) 682 328
668 Tretinoin (INN) (retinoic acid and its salts) — 375
669 Triamterene (INN) and its salts 540 275
670 Triaziridin-1-ylphosphine sulphide 654, 683 310
671 2,2,2-Tribromoethanol 672 326
672 Tribromoethyl alcohol 671 326
673 3,4,5-Tribromosalicylanilide (Tribromsalan) — 373
674 Trichlormethine (INN) and its salts 678 327
675 Trichloroacetic acid — 10
676 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane 182, 213 123
677 2,2,2-Trichloroethane-1,1-diol 146 77
678 Tri(β-chloroethyl)amine and its salts 674 327
679 Trichloromethane 156 366
680 N-(Trichloromethylthio)-4-cyclohex-4-ene-1,2-dicarboximide (Captan) 132 370
681 Tricresyl phosphate 694 277
682 2,4,6-Triethyleneimino-1,3,5-triazine 667 328
683 N,N,N-Triethylenethiophosphamide 654, 670 310
684 Trifluoperazine (INN) and its salts (521) 320
685 Trifluperidol (INN) 323 188
686 3,3',5-Triiodothyroacetic acid and its salts 368 5
687 3,4,5-Trimethoxyphenethylamine and its salts 415 222
688 2-2-6-Trimethyl-4-piperidyl benzoate and its salts 74 51
689 2,4,6-Trinitrophenol 375, 550 268
690 Trioxysalan (INN) (except natural content ofessences) 332, 333, 434 358
691 Triparanol (INN) 233 92
692 Tripelennamine (INN) 92, 581 347
693 1,2,3-Tris(2-triethylammonium-ethoxy)benzene triiodide 336 329
694 Tritolyl phosphate 681 277
695 Tuaminoheptane (INN), its isomers and salts 31 27
696 Urginea scilla Stern. and its galenical preparations 600 330
697 Vaccines, toxins and serums listed in the Annex to Council Directive No. 75/319/EEC — 323
698 Valnoctamide (INN) 313 184
699 Veratrine, its salts and galenical preparations — 331
700 Veratrum spp and their preparations — 333
701 Vinyl chloride monomer — 334
702 Vinylidene chloride 7, 227 126
703 Vitamins D2 and D3 174, 295 335
704 Warfarin (ISO) and its salts 2,372 203
705 Xanthates 16 336
706 Xanthinol 367 135
707 Xylidines, their isomers, salts and halogenated and sulphonated derivatives 41 33
708 Xylometazoline (INN) and its salts 629 313
709 Yohimbine and its salts — 337
710 Zoxazolamine (INN) 29 24

SCHEDULE 2
LIST OF SUBSTANCES WHICH COSMETIC PRODUCTS MUST NOT CONTAIN EXCEPT SUBJECT TO RESTRICTIONS
Regulations 4(3) and 6(1)
In this Schedule, the matters specified in columns 3, 4, 5 and 6 which apply to a particular substance are those set out to the right of its name as mentioned in column 2; and the matters specified in columns 4, 5 and 6 which apply in any particular case are those set out to the right of the matter specified in column 3 which applies in that case. The substance may not be used except for the purposes or contained other than in the types of product specified in column 3. The concentration of the substance in a product may not exceed the limit specified in column 4: where the names of two or more substances are mentioned in a single item as set out in column 2 and a product contains more than one of those substances, the limit specified in column 4 is the limit for all of those substances taken together; and where a product is intended to be mixed with another product in specified proportions before use, the level of concentration shall be calculated by reference to the mixture. Other requirements are specified in column 5. In column 4 of this Schedule, the percentage concentration is measured by reference to mass (m/m) unless a contrary intention appears.

PART I substances listed in annex iii, part i of the directive as substances which cosmetic products must not contain except subject to the restrictions laid down

(1) (2) (3) (4) (5) (6)
Reference Number Name of substance Purpose of substance or type of product Maximum concentration of substance in product Other requirements Required information
1 Boric acid Talcum powder 5 per cent Not to be used in products intended for children less than three years old Not to be used for children under three years of age
  Oral hygiene products 0.5 per cent — —
  Other products 3 per cent — —
2 (a) Thioglycollic acid, its salts and esters Hair waving or straightening products for general use 8 per cent (calculated as thioglycollic acid) ready for use pH value 7 to 9.5 Contains thioglycollate. Follow the instructions. Keep out of reach of children. For professional use only (where applicable)
  Hair waving or straightening products for professional use 11 per cent (calculated as thioglycollic acid) ready for use pH value 7 to 9.5
  Depilatories 5 per cent (calculated as thioglycollic acid) ready for use pH value 7 to 12.7
  Other hair care products which are removed after application 2 per cent (calculated as thioglycollic acid) ready for use pH value 7 to 9.5The directions for use drawn up in national or official languages must incorporate the following instructions—Avoid contact with eyes. In the event of contact with the eyes rinse immediately with plenty of water and seek medical advice. Wear suitable gloves (this latter instruction does not apply to Depilatories)
 (b) Thioglycollic acid esters Hair waving or straightening products for general use 8 per cent (calculated as thioglycollic acid) ready for use pH value 6 to 9.5
  Hair waving or straightening products for professional use 11 per cent (calculated as thioglycollic acid) ready for use pH value 6 to 9.5The directions for use drawn up in national or official languages must incorporate the following instructions—May cause sensitisation in the event of contact with the skin. Avoid contact with eyes. In the event of contact with the eyes rinse immediately with plenty of water and seek medical advice. Wear suitable gloves
3 Oxalic acid, its esters and alkaline salts Hair care products 5 per cent — For professional use only
4 Ammonia All purposes and products 6 per cent calculated as NH3 — Contains ammonia (not required when concentration is not more than 2 per cent)
5 Tosylchloramide Sodium All purposes and products 0.2 per cent — —
6 Chlorates of alkali metals Toothpaste 5 per cent — —
Other uses 3 per cent — —
7 Dichloromethane All purposes and products 35 per cent (and when mixed with 1,1,1-trichloroethane, total concentration must not exceed 35 per cent) Purity of the dichloromethane must be not less than 99.8 per cent —
8 m-andp-Phenylenediamines, theirN-substituted derivativesand their salts;N-substituted derivatives ofo-phenylenediamines Oxidizing colouring agents for hair dyeing for general use 6 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below — Contains phenylenediamines. Can cause an allergic reaction. Sensitivity test advisable before use. Do not use to dye eyelashes or eyebrows
Oxidizing colouring agents for hair dyeing for professional use 6 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below — Contains phenylenediamines. For professional use only. Can cause an allergic reaction. Sensitivity test advisable before use
9 Methylphenylenediamines (other than 4-methyl—m-phenylenediamine and its salts), theirN-substituted derivatives and their salts Oxidizing colouring agents for hair dyeing for general use 10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below — Contains phenylenediamines. Can cause an allergic reaction. Sensitivity test advisable before use. Do not use to dye eyelashes or eyebrows
Oxidizing colouring agents for hair dyeing for professional use 10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below — Contains phenylenediamines. For professional use only. Can cause an allergic reaction. Sensitivity test advisable before use
10 Diaminophenols Oxidizing colouring agents for hair dyeing for general use 10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below — Contains diaminophenols. Can cause an allergic reaction. Sensitivity test advisable before use. Do not use to dye eyelashes or eyebrows
Oxidizing colouring agents for hair dyeing for professional use 10 per cent calculated as a free base, subject to the provisions of “Combination Rule A” set out below — Contains diaminophenols. For professional use only. Can cause allergic reaction. Sensitivity test advisable before use
11 Dichlorophen All purposes and products 0.5 per cent — Contains dichlorophen
12 Hydrogen peroxide Hair care products preparations 12 per cent of H2O2 (40 volumes) — Contains hydrogen peroxide. Avoid contact with eyes. Rinse eyes immediately if product comes into contact with them
Skin hygiene preparations 4 per cent of H2O2 — Contains hydrogen peroxide. Avoid contact with eyes. Rinse eyes immediately if product comes into contact with them
Nail hardening preparations 2 per cent of H2O2 — Contains hydrogen peroxide. Avoid contact with eyes. Rinse eyes immediately if product comes into contact with them
13 Formaldehyde (See also Part I of Schedule 4) Nail hardeners 5 per cent — Contains formaldehyde. Protect cuticles with grease or oil. (Not required when concentration is not more than 0.05 per cent)
14 Hydroquinone Oxidizing colouring agent for hair dyeing for general use 2 per cent subject to the provision of “Combination Rule B” set out below — Contains hydroquinone. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them
Oxidizing colouring agent for hair dyeing for professional use 2 per cent subject to the provisions of “Combination Rule B” set out below — Contains hydroquinone. For professional use only. Rinse eyes immediately if product comes into contact with them
Agents for localised skin lightener 2 per cent — Contains hydroquinone. Avoid contact with eyes. Apply to small areas. If irritation develops discontinue use. Do not use on children under the age of 12
15 Potassium and sodium hydroxide Nail cuticle solvent 5 per cent calculated as sodium hydroxide — Contains alkali. Avoid contact with eyes. Can cause blindness. Keep out of reach of children
Hair straightener for general use 2 per cent calculated as sodium hydroxide — Contains alkali. Avoid contact with eyes. Can cause blindness. Keep out of reach of children
Hair straightener for professional use 4.5 per cent calculated as sodium hydroxide — For professional use only. Avoid contact with eyes. Can cause blindness
pH adjuster for depilatories — pH value not to exceed 12.7 Keep out of reach of children. Avoid contact with eyes
Other uses as pH adjuster — pH value not to exceed 11 Keep out of reach of children. Avoid contact with eyes
16 α-Naphthol Colouring agent for hair dyeing 0.5 per cent — Contains α-naphthol
17 Sodium nitrite Rust inhibitor 0.2 per cent Do not use with secondary and/or tertiary amines or other substances forming nitrosamines —
18 Nitromethane Rust inhibitor 0.3 per cent — —
19 Phenol and its alkali salts Soaps and shampoos 1 per cent calculated as phenol — Contains phenol
20 Pyrogallol Oxidizing colouring agent for hair dyeing for general use 5 per cent subject to the provisions of “Combination Rule B” set out below — Contains pyrogallol. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them
Oxidizing colouring agent for hair dyeing for professional use 5 per cent subject to the provisions of “Combination Rule B” set out below — Contains pyrogallol. For professional use only. Rinse eyes immediately if product comes into contact with them
21 Quinine and its salts Shampoos 0.5 per cent calculated as quinine base — —
Hair lotions 0.2 per cent calculated as quinine base — —
22 Resorcinol Oxidizing colouring agent for hair dyeing for general use 5 per cent subject to the provisions of “Combination Rule B” set out below — Contains resorcinol. Rinse hair well after application. Do not use to dye eyelashes or eyebrows. Rinse eyes immediately if product comes into contact with them
Oxidizing colouring agent for hair dyeing for professional use 5 per cent subject to the provisions of “Combination Rule B” set out below — Contains resorcinol. For professional use only. Rinse eyes immediately if product comes into contact with them
Hair lotions and shampoos 0.5 per cent subject to the provisions of “Combination Rule B” set out below — Contains resorcinol
23 (a) Alkali sulphides Depilatories 2 per cent calculated as sulphur pH value not to exceed 12.7 Keep out of reach of children. Avoid contact with eyes
(b) Alkaline earth sulphides Depilatories 6 per cent calculated as sulphur pH value not to exceed 12.7 Keep out of reach of children. Avoid contact with eyes
24 Water-soluble zinc salts with the exception of zinc 4-hydroxybenzenesulphonate All purposes and products 1 per cent calculated as zinc — —
25 Zinc 4-hydroxybenzenesulphonate Deodorants, antiperspirants and astringent lotions 6 per cent calculated as percentage of anhydrous substance — Avoid contact with eyes
26 Ammonium monofluorophosphate Oral hygiene products 0.15 per cent calculated as fluorine. When mixed with other fluorine compounds total fluorine concentration must not exceed 0.15 per cent — Contains ammonium monofluorophosphate
27 Sodium monofluorophosphate Oral hygiene products As for ammonium monofluorophosphate — Contains sodium monofluorophosphate
28 Potassium monofluorophosphate Oral hygiene products As for ammonium monofluorophosphate — Contains potassium monofluorophosphate
29 Calcium monofluorophosphate Oral hygiene products As for ammonium monofluorophosphate — Contains calcium monofluorophosphate
30 Calcium fluoride Oral hygiene products As for ammonium monofluorophosphate — Contains calcium fluoride
31 Sodium fluoride Oral hygiene products As for ammonium monofluorophosphate — Contains sodium fluoride
32 Potassium fluoride Oral hygiene products As for ammonium monofluorophosphate — Contains potassium fluoride
33 Ammonium fluoride Oral hygiene products As for ammonium monofluorophosphate — Contains ammonium fluoride
34 Aluminium fluoride Oral hygiene products As for ammonium monofluorophosphate — Contains aluminium fluoride
35 Stannous fluoride Oral hygiene products As for ammonium monofluorophosphate — Contains stannous fluoride
36 Hexadecyl ammonium fluoride Oral hygiene products As for ammonium monofluorophosphate — Contains hexadecyl ammonium fluoride
37 3-(n-Hexadecyl-N-2-hydroxyethylammonio)propyl-bis(2-hydroxyethyl)ammonium difluoride Oral hygiene products As for ammonium monofluorophosphate — Contains 3-(n-hexadecyl-N-2-hydroxyethylammonio)propyl-bis(2-hydroxyethyl)ammonium difluoride
38 NN'N'-Tris(polyoxyethylene)—N-hexadecylpropylenediamine dihydrofluoride Oral hygiene products As for ammonium monofluorophosphate — ContainsNN'N'-tris(polyoxyethylene)—N-hexadecylpropylenediamine dihydrofluoride
39 Octadecenyl ammonium fluoride Oral hygiene products As for ammonium monofluorophosphate — Contains octadecenyl ammonium fluoride
40 Sodium fluorosilicate Oral hygiene products As for ammonium monofluorophosphate — Contains sodium fluorosilicate
41 Potassium fluorosilicate Oral hygiene products As for ammonium monofluorophosphate — Contains potassium fluorosilicate
42 Ammonium fluorosilicate Oral hygiene products As for ammonium monofluorophosphate — Contains ammonium fluorosilicate
43 Magnesium fluorosilicate Oral hygiene products As for ammonium monofluorophosphate — Contains magnesium fluorosilicate
44 1,3-Bis(hydroxymethyl)-imidazolidene-2-thione Hair care preparations 2 per cent Not to be used in aerosol dispensers Contains 1,3-Bis(hydroxymethyl)imidazoli-dene-2-thione
Nail care preparations 2 per cent pH as applied value must be less than 4 Contains 1,3-Bis(hydroxymethyl)imidazoli-dene-2-thione
45 Benzyl alcohol (See also Part I of Schedule 4) Solvent, perfumes and flavourings — — —
46 6-Methylcoumarin Oral hygiene products 0.003 per cent — —
47 Nicomethanol hydrofluoride Oral hygiene products As for ammonium monofluorophosphate — Contains nicomethanol hydrofluoride
48 Silver nitrate Products to dye eyelashes or eyebrows 4 per cent — Contains silver nitrate. Rinse eyes immediately if product comes into contact with them
49 Selenium disulphide Anti-dandruff shampoos 1 per cent — Contains selenium disulphide. Avoid contact with eyes or damaged skin
50 Aluminium zirconium chloride hydroxide complexes AlxZr(OH)yCLz and the aluminium zirconium chloride hydroxide glycine complexes Anti-perspirants 20 per cent as anhydrous aluminium zirconium chloride hydroxide 5.4 per cent as zirconium The ratio of the number of aluminium atoms to that of zirconium atoms must be betweeen 2 and 10The ratio of the number of (Al+Zr) atoms to chlorine atoms must be between 0.9 and 2.1Not to be used in aerosol dispensers (sprays) Do not apply to irritated or damaged skin
51 Quinolin-8-ol and bis(8-hydroxy-quinolinium sulphate) (See also Part II of this Schedule) Stabilizer for hydrogen peroxide in rinse-off hair care preparations 0.3 per cent calculated as base — —
Stabilizer for hydrogen peroxide in non-rinse-off hair care preparations 0.03 per cent calculated as base — —
52 Methanol Denaturant for ethanol and isopropyl alcohol 5 per cent calculated as a percentage of ethanol and isopropyl alcohol — —
53 Etidronic acid and its salts (1-hydroxy-ethylidene-diphosphonic acid and its salts) Hair care 1.5 per cent expressed as etidronic acid — —
Soap 0.2 per cent expressed as etidronic acid — —
54 1-Phenoxypropan-2-ol (See also Part I of Schedule 4) Products rinsed off after use. Prohibited in oral hygiene products 2 per cent — —
Combination Rules
1. Where a cosmetic product contains two or more substances to which this Combination Rule applies, the concentration in the product of each of those substances shall be such that the sum of the relevant quotients for those substances (as defined in Rule C below) shall not exceed 1.
2. Where a cosmetic product contains the substances to which this Combination Rule applies, the concentration in the product of each of those substances shall be such that the sum of the relevant quotients for those substances (as defined in Rule C below) shall not exceed 2; but the concentration of each substance shall not in any event exceed the limit specified for the substance in respect of the product in column 4 above.
3. The relevant quotient for each substance is the actual concentration of the substance in the product divided by the maximum concentration specified for the substance in respect of the product in Column 4 of this Schedule.
PART II substances listed in annex iii, part 2 (formerly annex iv, part i) of the directive as substances provisionally allowed

(1) (2) (3) (4) (5) (6) (7)
Reference Number Name of substance Purpose of substance or type of product Maximum concentration of substance in product Other requirements Required information Permitted for use until
1 Quinolin-8-ol and bis(8 hydroxy-quinolium)-sulphate (See also Part I of this Schedule) Skin hygiene products not rinsed off after use 0.02 per cent calculated as base — Contains Quinolin-8-ol 31.12.1990
  Foot hygiene products not rinsed off after use 0.04 per cent calculated as base —
  Mouth hygiene products 0.01 per cent calculated as base —
2 1,1,1-Trichloroethane (methyl chloroform) Aerosol Spray 35 per cent (and when mixed with dichloromethane total concentration must not exceed 35 per cent) — Do not spray on a naked flame or any incandescent material 31.12.1989
3 ENTRY DELETED — — — — —
4 2,2'-Dithiobis (pyridine 1-oxide), addition product with magnesium sulphate trihydrate Rinsed-off hair care products 1 per cent — — 31.12.1989
5 ENTRY DELETED
PART III substances excluded from the scope of the directive (mentioned in annex v)

(1) (2) (3) (4) (5) (6)
Reference Number Name of substance Purpose of substance or type of product Maximum concentration of substance in product Other requirements Required information
1 Lead acetate Hair care products 3 per cent — Contains lead acetate. Wash hands after use. Do not use on broken or abraded skin. Keep out of reach of children
2 Thiomersal and phenylmercuric compounds To preserve concentrated shampoos and hair creams which contain non-ionic emulsifiers which render other preservatives ineffective 0.003 per cent calculated as mercury. When mixed with other mercury compounds the total mercury concentration must not exceed 0.007 per cent — —
SCHEDULE 3
LIST OF COLOURING AGENTS WHICH COSMETIC PRODUCTS MUST NOT CONTAIN EXCEPT SUBJECT TO RESTRICTIONS AND EXCEPT COLOURING AGENTS INTENDED SOLELY TO COLOUR HAIR
Regulation 4(4)
In this Schedule the colouring agents referred to in regulation 4(4)(a) are–
(i) those identified in column 1 either by name or by colour index number (the colour index numbers being those specified in the third edition of The Colour Index published in 1971 by the Society of Dyers and Colourists);
(ii) lakes or salts of these colouring agents which do not use substances prohibited under Annex II or which are excluded under Annex V from the scope of the Directive.
In the case of colouring agents identified by the addition of (*) to the name or colour index number, the insoluble barium, strontium and zirconium lakes, salts and pigments of these colouring agents shall also be permitted. They must pass the test for insolubility which will be determined by the procedure laid down in Article 8 of the Directive.
Colouring agents whose number is preceded by the letter “E” in accordance with the EEC Directive of 23 October 1962 on the approximation of the rules of member States concerning foodstuffs and colouring matter, as amended, and adapted must fulfil the purity requirements laid down in those Directives. They continue to be subject to the general criteria set out in Annex III to the 1962 Directive concerning colouring matters where the letter “E” has been deleted therefrom.

PART I colouring agents listed in annex iv part 1 (formerly annex iii part 2) of the directive as colouring agents which cosmetic products must not contain except subject to the restrictions laid down
Field of application
In column 3 of this Schedule, the entry “X” in a sub-column means that the colouring agent must not be used other than as follows–
 Sub-column 1=Colouring agents allowed in all cosmetic products;
 Sub-column 2=Colouring agents allowed in all cosmetic products except those intended to be applied in the vicinity of the eyes, in particular eye make-up and eye make-up remover;
 Sub-column 3=Colouring agents allowed exclusively in cosmetic products except cosmetic products intended to come into contact with the mucous membranes;
 Sub-column 4=Colouring agents allowed exclusively in cosmetic products intended to come into contact only briefly with the skin.

(1) (2) (3) (4)
  Type of productField of application
Name or colour index number Colour 1 2 3 4 Other requirements
10006 Green    X
 10020 Green   X
10316* Yellow  X
11680 Yellow   X
11710 Yellow   X
11725 Orange    X
11920 Orange X
12010 Red   X
12075* Orange X
12085* Red X    3 per cent maximum concentration in the finished product
12120 Red    X
12150 Red X
12370 Red    X
12420 Red    X
12480 Brown    X
12490 Red X
12700 Yellow    X
13015 Yellow X    E 105
13065(1)
14270 Orange X    E 103
14700 Red X
14720 Red X    E 122
14815 Red X    E 125
15510* Orange  X
15525 Red X
15580 Red X
15585* Red  X
15620 Red    X
15630* Red X    3 per cent maximum concentration in the finished product
15800 Red   X
15850* Red X
15865* Red X
15880 Red X
15980 Orange X    E 111
15985* Yellow X    E 110
16035 Red X
16185 Red X    E 123
16230 Orange   X
16255* Red X    E 124
16290 Red X    E 126
17200 Red X
18050 Red   X
18130 Red    X
18690 Yellow    X
18736 Red    X
18820 Yellow    X
18965 Yellow X
19140* Yellow X    E 102
20040 Yellow    X Maximum 3,3'-dimethylbenzidine concentration in the colouring agent: 5 ppm
20170 Orange   X
20470 Black    X
21100 Yellow    X Maximum 3,3'-dichlorobenzidine concentration in the colouring agent: 5 ppm
21108 Yellow    X Maximum 3,3'dichlorobenzidine concentration in the colouring agent: 5 ppm
21230 Yellow   X
24790 Red    X
27290* Red    X
27755 Black X    E152
28440 Black X    E151
40215 Orange    X
40800 Orange X
40820 Orange X    E 160e
40825 Orange X    E 160f
40850 Orange X    E 161g
42045 Blue    X See also Part II
42051* Blue X    E 131
42053 Green X    
42080 Blue    X
42090 Blue X
42100 Green    X
42170 Green    X
42510 Violet   X
42520 Violet    X 5 ppm maximum concentration in the finished product
42640 Violet X
42735 Blue   X
44045 Blue    X See also Part II
44090 Green X    E 142
45100 Red    X
45170* Red X
45170:1 Red  X
45190 Violet    X
45220 Red    X
45350 Yellow X    6 per cent maximum concentration in the finished product
45370* Orange X    Not more than 1 per cent 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid and 2 per cent 2-(bromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
45380* Red X    as immediately above
45396 Orange X    When used in lipstick, thecolouring agent is allowed only in free acid form and in a maximum concentration of 1 per cent
45405 Red  X   Not more than 1 per cent 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid and 2 per cent 2-(bromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
45410* Red X    as immediately above
45425 Red X    Not more than 1 per cent 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid and 3 per cent 2-(iodo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
45430* Red X    as immediately above E 127
47000 Yellow   X
47005 Yellow X    E 104
50325 Violet    X
50420 Black   X
51319 Violet    X
58000 Red X
59040 Green   X
60724 Violet    X
60725 Violet X
60730 Violet   X
61565 Green X
61570 Green X
61585 Blue    X
62045 Blue    X
69800 Blue X    E 130
69825 Blue X
71105 Orange   X
73000 Blue X
73015 Blue X    E 132
73360 Red X
73385 Violet X
73900 Violet    X See also Part II
73915 Red    X
74100 Blue    X
74160 Blue X
74180 Blue    X See also Part II
74260 Green  X
75100 Yellow X
75120 Orange X    E 160b
75125 Yellow X    E 160d
75130 Orange X    E 160a
75135 Yellow X    E 161d
75170 White X
75300 Yellow X    E 100
75470 Red X    E 120
75810 Green X    E 140 and E 141
77000 White X    E 173
77002 White X
77004 White X
77007 Blue X
77015 Red X
77120 White X
77163 White X
77220 White X    E 170
77231 White X
77266 Black X
77267 Black X
77268:1 Black X    E 153
77288 Green X    Free from chromate ions
77289 Green X    Free from chromate ions
77346 Green X
77400 Brown X
77480 Brown X    E 175
77489 Orange X    E 172
77491 Red X    E 172
77492 Yellow X    E 172
77499 Black X    E 172
77510 Blue X    Free from cyanide ions
77713 White X
77742 Violet X
77745 Red X
77820 White X    E 174
77891 White X    E 171
77947 White X
Acid red 195 Red   X
Aluminium, Zinc, magnesium and calcium stearates White X
Anthocyanins Red X    E 163
Beetroot red Red X    E 162
Bromocresol green Green    X
Bromothymol blue Blue    X
Caramel Brown X    E 150
Capsanthin capsorubin Orange X    E 160c
Lactoflavin Yellow X    E 101

PART II colouring agents listed in annex iv part 2 of the directive as colouring agents which cosmetic products must not contain except subject to the restrictions laid down and where cosmetic product supplied before a certain date
Field of application
In column 3 of this Schedule, the entry “X” in a sub-column means that the colouring agent must not be used other than as follows–
 Sub-column 1=Colouring agents allowed in all cosmetic products;
 Sub-column 2=Colouring agents allowed in all cosmetic products except those intended to be applied in the vicinity of the eyes, in particular eye make-up and eye make-up remover;
 Sub-column 3=Colouring agents allowed exclusively in cosmetic products intended not to come into contact with the mucous membranes;
 Sub-column 4=Colouring agents allowed exclusively in cosmetic products intended to come into contact only briefly with the skin.

(1) (2) (3) (4) (5)
  Type of productField of application
Name or colour index number Colour 1 2 3 4 Other requirements Cosmetic product supplied until
13065 Yellow   X   31.12.1989
15800(1)
19120(1)
20470(1)
21110 Orange    X Maximum 3,3-dichlorobenzidine concentration in the colouring agent: 5 ppm 31.12.1989
21115(1)
26100 Red  X    31.12.1989
42045 Blue   X  See also Part I 31.12.1989
42170(1)
42535 Violet   X  Solely in hair preparations at a maximum concentration of 100 ppm 31.12.1989
44045 Blue   X  See also Part I 31.12.1989
45190(1)
47000(1)
61554 Blue   X  Only in hair-care preparations in a maximum concentration of 50 ppm 31.12.1989
73900 Violet   X  See also Part I 31.12.1989
73905(1)
74180 Blue   X  See also Part I 31.12.1989
75660(1)

SCHEDULE 4
LIST OF PRESERVATIVES WHICH COSMETIC PRODUCTS MUST NOT CONTAIN EXCEPT SUBJECT TO RESTRICTIONS
Regulations 4(5) and 6(1)
In this Schedule, the matters specified in columns 3, 4, 5 and 6 which apply to a particular substance are those set out to the right of its name as mentioned in column 2; and the matters specified in columns 4, 5 and 6 which apply in any particular case are those set out to the right of the matter specified in column 3 which applies in that case. The substance may not be used or contained other than in the types of product specified in column 3. The concentration of the substance, when it is used as a preservative, in a product may not exceed the limit set out in column 4. Where a product is intended to be mixed with another product in specified proportions before use, the level of concentration shall be calculated by reference to the mixture. Other requirements are specified in column 5.
In column 4 of this Schedule, “A” indicates that the concentration of the substance in a product may exceed the limit set out in that column provided that–
(a) the presence of any excess of the substance in a product over the concentration so set out is not for the primary purpose of inhibiting the development of micro-organisms; and
(b) the purpose for which any such excess is present in the product is apparent from the labelling of the product.
In this Schedule–
 “salts” means salts of the cations sodium, potassium, calcium, magnesium, ammonium and ethanolamines and of the anions chloride, bromide, sulphate and acetate;
 “esters” means esters of methyl, ethyl, propyl, isopropyl, butyl, isobutyl and phenyl.
In column 4 of this Schedule, the percentage concentration is measured by reference to mass (m/m) unless a contrary intention appears.
All preservative substances containing formaldehyde or any substances named in this Schedule which release formaldehyde must be labelled with the warning “contains formaldehyde” when the concentration of formaldehyde in the final product exceeds 0.05 per cent.

PART I preservatives listed in annex vi, part i of the directive as preservatives which cosmetic products may not contain except subject to the restrictions laid down

(1) (2) (3) (4) (5) (6)
Reference Number Name of substance Purpose of substance or type of product Maximum concentration of substance in product Other requirements Required information
1 Benzoic acid, its salts and esters All products 0.5 per cent (acid)A — —
2 Propionic acid and its salts All products 2 per cent (acid)A — —
3 Salicylic acid and its salts All products 0.5 per cent (acid)A Not to be used in preparations for children under three years of age except for shampoos Not to be used for children under three years of age (Solely for products which might be used for children under three years of age and which remain in prolonged contact with the skin)
4 Sorbic acid (hexa-2,4-dienoic acid) and its salts All products 0.6 per cent (acid)A — —
5 Formaldehyde and paraformaldehyde For oral hygiene 0.1 per cent (concentrations expressed as free formaldehyde) Not to be used in aerosol dispensers (sprays) —
  Except for oral hygiene (see also Part I of Schedule 2) 0.2 per cent (concentrations expressed as free formaldehyde)
6 Hexachlorophene (INN) (1)
7 Biphenyl-2-ol (o-phenylphenol) and its salts All products 0.2 per cent expressed as the phenolA — —
8 Pyrithione zinc (INN) Products rinsed off after use 0.5 per centA Not to be used in oral hygiene products —
9 Inorganic sulphites and hydrogen sulphites All products 0.2 per cent expressed as free SO2A — —
10 Sodium iodate Products rinsed off after use 0.1 per cent — —
11 Chlorobutanol (INN) All products 0.5 per cent Not to be used in aerosol dispensers (sprays) Contains chlorobutanol
12 4-Hydroxybenzoic acid and its salts and esters All products 0.4 per cent (acid) for 1 ester, 0.8 per cent (acid) for mixtures of estersA — —
13 3-Acetyl-6-methylpyran-2,4-(3H)-dione (Dehydracetic acid) and its salts All products 0.6 per cent (acid) Not to be used in aerosol dispensers (sprays) —
14 Formic acid All products 0.5 per cent (acid)A — —
15 3,3'-Dibromo-4,4'-hexamethylene-dioxydibenzamidine-(Dibromohexamidine) and its salts (including isethionate) All products 0.1 per cent — —
16 Thiomersal (INN) Eye make-up and eye make-up remover 0.007 per cent calculated as mercury. When mixed with other authorised mercury compounds total mercury concentration must not exceed 0.007 per cent — Contains thiomersal
17 Phenylmercuric salts (including borate) Eye make-up and eye make-up remover 0.007 per cent calculated as mercury. When mixed with other authorised mercury compounds total mercury concentration must not exceed 0.007 per cent — Contains phenylmercuric compounds
18 Undec-10-enoic acid and its salts All products 0.2 per cent (acid)A — —
19 Hexetidine (INN) Products rised off after use 0.1 per centA — —
20 5-Bromo-5-nitro-1,3-dioxane Products rinsed off after use 0.1 per cent Avoid formation of nitrosamines —
21 Bronopol (INN) All products 0.1 per centA Avoid formation of nitrosamines —
22 2,4-Dichlorobenzyl alcohol All products 0.15 per centA — —
23 Triclocarban (INN) All products 0.2 per centA Purity criteria: 3,3'4,4'-Tetrachloroazobenzene 1 ppm 3,3',4,4'-Tetrachloroazoxybenzene 1 ppm —
24 4-Chloro-m-cresol Not to be used in products intended to come into contact with mucous membranes 0.2 per centA — —
25 Triclosan (INN) All products 0.3 per centA — —
26 4-Chloro-3,5-xylenol All products 0.5 per centA — —
27 3,3'-Bis(1-hydroxymethyl-2,5-dioxoimidazolidin-4-yl)-1,1'-methylenediurea (“Imidazolidinyl urea”) All products 0.3 per centA — —
28 Poly(1-hexamethylene-biguanide hydrochloride) All products 0.3 per centA — —
29 2-Phenoxyethanol All products 1.0 per centA — —
30 Hexamethylenetetramine (methenamine (INN)) All products 0.15 per centA — —
31 Methenamine 3-chloroallylochloride (INNM) All products 0.2 per cent — —
32 1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-di-methylbutan-2-one All products 0.5 per centA — —
33 1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione All products 0.6 per centA — —
34 Benzyl alcohol (See also Part I of Schedule 2) All products 1.0 per centA — —
35 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone and its monoethanolamine salt Products rinsed off after use 1.0 per centA — —
For other products 0.5 per centA — —
36 1,2-Dibromo-2,4-dicyanobutane All products 0.1 per cent Not to be used in cosmetic sunscreen products —
37 6,6-Dibromo-4,4-dichloro-2,2'-methylenediphenol (Bromochlorophen) All products 0.1 per centA — —
38 4-Isopropyl—m-cresol All products 0.1 per cent — —
39 Mixture of 5-Chloro-2-methylisothiazol-3(2H)-one and 2-methylisothiazol-3(2H)-one with magnesium chloride and magnesium nitrate All products 0.0015 per cent of a mixture in the ratio 3:1 of 5-chloro-2-methylisothiazol,3(2H)-one and 2-methylisothiazol-3(2H)-one — —
40 2-Benzyl-4-chlorophenol (Chlorophene) All products 0.2 per cent — —
41 2-Chloroacetamide All products 0.3 per cent — Contains chloroacetamide
42 Chlorhexidine (INN) and its digluconate, diacetate and dihydrochloride All products 0.3 per centA — —
43 1-Phenoxypropan-2-ol (see also Part I, of Schedule 2) Products rinsed off after use 1.0 per cent — —

PART II preservatives listed in annex vi part 2 of the directive as preservatives which cosmetic products may not contain except subject to the restrictions laid down and where supplied before a certain date

(1) (2) (3) (4) (5) (6) (7)
Reference Number in Annex VI Part 2 of the Directive Name of substance Purpose of substance or type of product Maximum concentration of substance in product Other requirements Required information Preservative supplied until
1 ENTRY DELETED (2)
2 Chlorphenesin (INN) (see note (1)) All products 0.3 per cent — — 31.12.1989
3 ENTRY DELETED (2)
4 Alkyl (C12–C22) trimethylammonium bromide and chloride (including Cetrimonium bromide (INN)) All products 0.1 per centA — — 31.12.1989
5 ENTRY DELETED (2)
6 4,4-Dimethyl-1,3-oxazolidine Products rinsed off after use 0.1 per cent The pH of the finished product shall not be lower than 6 — 31.12.1989
7 to 14 ENTRIES DELETED (2)
15 Benzethonium chloride (INN) Not to be used in products intended to come into contact with mucous membranes 0.1 per centA — — 31.12.1989
16 Benzalkonium chloride (INN) bromide and saccharinate All products 0.25 per centA — — 31.12.1989
17 1-[1,3-Bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea All products 0.5 per cent — — 31.12.1989
18 to 19 ENTRY DELETED (2)
20 Hexamidine (INN) and its salts (including isethionate and 4-hydroxybenzoate) All products 0.1 per centA — — 31.12.1989
21 Benzylhemiformal (a 1:1 mixture of benzyloxymethanol and (benzyloxymethoxy) methanol) All products 0.2 per cent — — 31.12.1989
22 to 25 ENTRIES DELETED (2)
26 Glutaraldehyde Prohibited in aerosols (sprays) 0.1 per cent Contains glutaraldehyde where the glutaraldehyde concentration in the finished product exceeds 0.05 per cent — 31.12.1991


SCHEDULE 5
LIST OF UV FILTERS WHICH COSMETIC PRODUCTS MUST NOT CONTAIN EXCEPT SUBJECT TO RESTRICTIONS
Regulations 4(6) and 6(1)
In this Schedule, the matters specified in columns 3, 4 and 5 which apply to a particular substance are those set out to the right of its name as mentioned in column 2. The concentration of the substance in a product may not exceed the limit specified in column 3. Where a product is intended to be mixed with another product in specified proportions before use, the level of concentration shall be calculated by reference to the mixture. Other requirements are specified in column 4. In column 3 of this Schedule, the percentage concentration is measured by reference to mass (m/m) unless a contrary intention appears.

PART I uv filters listed in annex vii, part i, of the directive as uv filters which cosmetic products may not contain except subject to the restrictions laid down

(1) (2) (3) (4) (5)
Reference Number Name of substance Maximum concentration of substance in product Other requirements Required information
1 4-Aminobenzoic acid 5 per cent — —
2 N,N,N-Trimethyl-4-(2-oxoborn-3-ylidenemethyl)anilinium methyl sulphate 6 per cent — —
3 Homosalate (INN) 10 per cent — —
4 Oxybenzone (INN) 10 per cent — Contains oxybenzone. (Not required when concentration is not more than 0.5 per cent, and when the substance is only intended to protect the product.)
5 3-Imidazol-4-ylacrylic acid and its ethyl ester 2 per cent (expressed as acid) — —
6 2-Phenylbenzimidazole-5-sulphonic acid and its potassium, sodium and triethanolamine salts 8 per cent (expressed as acid) — —
PART II uv filters listed in annex vii, part 2 of the directive as uv filters which cosmetic products may not contain except subject to the restrictions laid down and where supplied before a certain date

(1) (2) (3) (4) (5) (6)
Reference Number Name of substance Maximum concentration of substance in product Other requirements Required information UV filter supplied until
1 N-Propoxylated ethyl 4—bis aminobenzoate, mixed isomers 5 per cent — — 31.12.1991
2 Ethoxylated ethyl 4-aminobenzoate 10 per cent — — 31.12.1991
3 ENTRY DELETED
4 Glycerol 1-(4-aminobenzoate) 5 per cent Must not contain any benzocaine (INN) — 31.12.1991
5 2-Ethylhexyl 4-dimethylaminobenzoate 8 per cent — — 31.12.1991
6 2-Ethylhexyl salicylate 5 per cent — — 31.12.1991
7–11 ENTRIES DELETED
12 Isopentyl 4-methoxycinnamate mixed isomers 10 per cent — — 31.12.1991
13 2-Ethylhexyl 4-methoxycinnamate 10 per cent — — 31.12.1991
14–15 ENTRIES DELETED
16 2-Hydroxy-4-methoxy-4-methylbenzophenone (Mexenone) 4 per cent — Contains Mexenone (Not required when concentration is not more 0.5 per cent and when the substance is only intended to protect the product) 31.12.1991
17 2-Hydroxy-4-methoxybenzophenone-5 sulphonic acid and sodium salt (Sulisobenzone and Sulisobenzone sodium) 5 per cent (expressed as acid) — — 31.12.1991
18–23 ENTRIES DELETED
24 α-(2-Oxoborn-3-ylidene)-toluene-4-sulphonic acid and its salts 6 per cent (expressed as acid) — — 31.12.1991
25 3-(4-Methylbenzylidene)-d-1-camphor 6 per cent — — 31.12.1991
26 3-Benzylidene camphor 6 per cent — — 31.12.1991
27 ENTRY DELETED
28 4-Isopropyl dibenzoylmethane 5 per cent — — 31.12.1991
29 4-Isopropylbenzyl salicylate 4 per cent — — 31.12.1991
30 ENTRY DELETED
31 1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)propane 1,3-dione 5 per cent — — 31.12.1991
32 2,4,6-Trianilino-(p-carbo-2' ethylhexyl-1'-oxi)-1,3,5-triazine 5 per cent — — 31.12.1991
SCHEDULE 6
SAMPLING AND TESTING
Regulation 9
1 
In this Schedule–
 “Annex A” means the Annex to Commission Directive No. 80/1335/EEC, as amended by Commission Directive No. 87/143/EEC;
 “Annex B” means the Annex to Commission Directive No. 82/434/EEC;
 “Annex C” means the Annex to Commission Directive No. 83/514/EEC;
 “Annex D” means the Annex to Commission Directive No. 85/490/EEC;
 “purchase” means purchase for the purpose of carrying out a test.
2 
An enforcement authority intending to purchase a cosmetic product shall purchase a sufficient laboratory sample, as defined in paragraph 2.3 of Part I of Annex A, for the purpose of Annex A; and, for the purposes of the definition of “total sample” in paragraph 2.2 of Part I of Annex A, samples shall be regarded as having the same batch number if:
(a) the means of identifying the batch referred to in regulation 6(1)(g) above shows that they were manufactured in the same batch; or
(b) in the case of a product not manufactured in a batch, the reference referred to in regulation 6(1)(g) above shows that they are derived from the same unit of production; or
(c) in the case of a product which does not comply with the requirements of regulation 6(1)(g) above, the officer effecting the purchase has reasonable cause to believe that they were manufactured in the same batch or are derived from the same unit of production, as the case may be.
3 
The immediate container, if any, of a cosmetic product purchased by an enforcement authority shall not have been opened by, on behalf of or at the request of the enforcement authority before the purchase takes place and the container shall not thereafter be opened except in accordance with paragraph 5.3 of Part I of Annex A and paragraph 1.2 of Part II of Annex A.
4 
As soon as an enforcement authority has purchased a cosmetic product, the officer effecting the purchase shall–
(a) either–
(i) place a seal on the product’s container or outer packaging, or
(ii) place the product in a container and forthwith place a seal on that container, in such a way that the product’s immediate container cannot be opened or (in the case of a product which was not in a container when it was purchased) the product cannot be touched without (in either case) the seal being broken in such a manner that it would be apparent thereafter that it had been broken, and
(b) attach to the product a label indicating–
(i) the name of the product,
(ii) the date, time and place at which the product was purchased,
(iii) his own name, and
(iv) the name of the enforcement authority making the purchase.
5 

(1) Subject to sub-paragraph (2) below, the provisions of Part I of Annex A, other than paragraphs 3.1, 3.2 and 4, and of Part II of Annex A, other than paragraph 1.4, shall be complied with in the sampling of cosmetic products and the laboratory preparation of test portions.
(2) Where, because of the way in which a cosmetic product is put up for sale, it is not practicable for Part II of Annex A to be complied with, it shall be prepared for testing in accordance with good analytical practice, and the person so preparing it shall record in writing the method of preparation which he has used.
6 

(1) Any test to determine whether a cosmetic product contains a significant amount of free sodium hydroxide or free potassium hydroxide shall be carried out in accordance with paragraphs 1 to 4 of Part III of Annex A.
(2) Any test to determine the amount of free sodium hydroxide or free potassium hydroxide in a hair straightener product or a nail cuticle solvent product shall be carried out in accordance with paragraphs 1, 2, 3 and 5 of Part III of Annex A.
(3) Any test to determine whether a hair-care product contains oxalic acid or any alkaline salt of oxalic acid or to determine the amount of such a substance in a hair-care product shall, subject to the limitation specified in the second sentence of paragraph 1 of Part IV of Annex A, be carried out in accordance with the said Part IV.
(4) Any test to determine the amount of chloroform in toothpaste shall, subject to the limitation specified in the second sentence of paragraph 1 of Part V of Annex A, be carried out in accordance with the said Part V.
(5) Any test to determine the amount of zinc chloride, zinc sulphate or zinc 4-hydroxybenzenesulphonate by virtue of their zinc contents in a cosmetic product shall be carried out in accordance with Part VI of Annex A and Commission Directive 87/143/EEC, and shall take into account paragraph 11 of Part VII of Annex A.
(6) Any test to determine whether a cosmetic product contained in an aerosol dispenser or a cream, emulsion, lotion, gel or oil intended to be applied to the skin contains 4-hydroxybenzenesulphonic acid, or to determine the amount of that acid in such a product, shall be carried out in accordance with Part VII of Annex A.
(7) Any test to determine whether a hair-care product contains persulphate, bromate or hydrogen peroxide shall be carried out in accordance with Part A of Part 1 of Annex B.
(8) Any test to determine whether a hair-care product contains barium peroxide shall be carried out in accordance with Part B of Part 1 of Annex B.
(9) Any test to determine the amount of hydrogen peroxide in a hair-care product shall be carried out in accordance with Part C of Part 1 of Annex B.
(10) Any test to determine whether a hair-dye contains any of the oxidation colorants specified in paragraph 1 of Part II of Annex B, or to determine the amount of such a substance in a hair-dye, shall be carried out in accordance with the said Part II.
(11) Any test to determine whether a cosmetic product contains nitrite, or to determine the amount of that substance in a cosmetic product, shall be carried out in accordance with Part III of Annex B.
(12) Any test to determine whether a cosmetic product contains free formaldehyde, or to determine the amount of that substance in a cosmetic product, shall be carried out in accordance with Part IV of Annex B.
(13) Any test to determine the amount of resorcinol in a shampoo or hair lotion shall, subject to the limitation specified in the second sentence of paragraph 1 of Part V of Annex B, be carried out in accordance with the said Part V.
(14) Any test to determine the amount of methanol in relation to ethanol or propan-2-ol in a cosmetic product shall be carried out in accordance with Part VI of Annex B.
(15) Any test to determine the amount of dichloromethane or 1,1,1-trichloroethane in a cosmetic product shall be carried out in accordance with paragraphs 1 to 10 of that part of Annex C which is headed “Determination of dichloromethane and 1,1,1-trichloroethane”.
(16) Any test to determine whether a cosmetic product contains quinolin-8-ol or bis(8-hydroxyquinolinium) sulphate, or to determine the amount of such a substance in a cosmetic product, shall be carried out in accordance with paragraphs 1 to 9 of that part of Annex C which is headed “Identification and determination of quinolin-8-ol and bis(8-hydroxyquinolinium) sulphate”.
(17) Any test to determine the amount of ammonia in a cosmetic product shall be carried out in accordance with paragraphs 1 to 8 of that part of Annex C which is headed “Determination of ammonia”.
(18) Any test to determine whether a cosmetic product contains nitromethane, or to determine the amount of that substance in a cosmetic product, shall be carried out in accordance with paragraphs 1 to 7 of that part of Annex C which is headed “Identification and determination of nitromethane”.
(19) Any test to determine whether a hair waving, hair straightening or depilatory product contains mercaptoacetic acid, or to determine the amount of that substance in such a product, shall be carried out in accordance with paragraphs 1 to 6 of that part of Annex C which is headed “Identification and determination of mercaptoacetic acid in hair-waving, hair-straightening and depilatory products”.
(20) Any test to determine whether a cosmetic product contains hexachlorophene (INN) shall be carried out in accordance with paragraphs 1 to 7 of Part A of that part of Annex C which is headed “Identification and determination of hexachlorophene”.
(21) Any test to determine the amount of hexachlorophene (INN) in a cosmetic product shall be carried out in accordance with paragraphs 1 to 9 of Part B of that part of Annex C which is headed “Identification and determination of hexachlorophene”.
(22) Any test to determine the amount of tosylchloramide sodium (INN) in a cosmetic product shall be carried out in accordance with paragraphs 1 to 9 of that part of Annex C which is headed “Quantitative determination of tosylchloramide sodium (INN) (chloramine-T)”.
(23) Any test to determine the total amount of fluorine in dental creams shall be carried out in accordance with paragraphs 1 to 8 of that part of Annex C which is headed “Determination of total fluorine in dental creams”.
(24) Any test to determine whether a cosmetic product contains organomercury compounds shall be carried out in accordance with paragraphs 1 to 4 of Part A of that part of Annex C which is headed “Identification and determination of organomercury compounds”.
(25) Any test to determine the amount of organomercury compounds in a cosmetic product shall be carried out in accordance with paragraphs 1 to 7 of Part B of that part of Annex C which is headed “Identification and determination of organomercury compounds”.
(26) Any test to determine the amount of alkali sulphides or alkaline earth sulphides in a cosmetic product shall be carried out in accordance with paragraphs 1 to 8 of that part of Annex C which is headed “Determination of alkali and alkaline earth sulphides”.
(27) Any test for the identification and determination of the amount of glycerol 1-(4-aminobenzoate) in a cosmetic product shall be carried out in accordance with that part of Annex D which is headed “Identification and determination of glycerol 1-(4-aminobenzoate)”.
(28) Any test to determine the amount of chlorobutanol (INN) in a cosmetic product shall be carried out in accordance with that part of Annex D which is headed “Determination of chlorobutanol”.
(29) Any test for the identification and determination of the amount of quinine in a cosmetic product shall be carried out in accordance with that part of Annex D which is headed “Identification and determination of quinine”.
(30) Any test for the identification and determination of inorganic sulphites and hydrogen sulphites in a cosmetic product shall be carried out in accordance with that part of Annex D which is headed “Identification and determination of inorganic sulphites and hydrogen sulphites”.
(31) Any test for the identification and determination of chlorates of the alkali metals in a cosmetic product shall be carried out in accordance with that part of Annex D which is headed “Identification and determination of chlorates of the alkali metals”.
(32) Any test for the identification and determination of sodium iodate in a cosmetic product shall be carried out in accordance with that part of Annex D which is headed “Identification and determination of sodium iodate”.
SCHEDULE 7
REVOCATIONS
Regulation 1(6)


(1) (2)
Regulations revoked References
The Cosmetic Products (Safety) Regulations 1984 S.I. 1984/1260
The Cosmetic Products (Safety) (Amendment) Regulations 1985 S.I. 1985/2045
The Cosmetic Products (Safety) (Amendment) Regulations 1987 S.I. 1987/1920
The Cosmetic Products (Safety) (Amendment) Regulations 1988 S.I. 1988/802
The Cosmetic Products (Safety) (Amendment No. 2) Regulations 1988 S.I. 1988/2121