
Article 1 
The preparations belonging to the group ‘Enzymes’, as specified in Annex I, are authorised for use without a time-limit as additives in animal nutrition under the conditions laid down in that Annex.
Article 2 
The preparations belonging to the group ‘Enzymes’, as specified in Annex II, are authorised for use for four years as additives in animal nutrition under the conditions laid down in that Annex.
Article 3 
The preparations belonging to the group ‘Micro-organisms’, as specified in Annex III, are authorised for use without a time-limit as additives in animal nutrition under the conditions laid down in that Annex.
Article 4 
This Regulation shall enter into force on the 20th day following its publication in the Official Journal of the European Union.
This Regulation shall be binding in its entirety and directly applicable in all Member States.Done at Brussels, 4 November 2005.
For the Commission
Markos KYPRIANOU
Member of the Commission
ANNEX I

EC No Additive Chemical formula, description Species or category of animal Maximum age Minimum content Maximum content Other provisions End of period of authorisation
Units of activity/kg of complete feedingstuff
Enzymes
E 1603 Endo-1,3(4)-beta-glucanaseEC 3.2.1.6 Preparation of endo-1,3(4)-beta-glucanase produced by Aspergillus aculeatus (CBS 589.94) having a minimum activity of:
 Coated form:
Endo-1,3(4)-beta-glucanase: 50 FBG/g
 Liquid form:
Endo-1,3(4)-beta-glucanase: 120 FBG/ml Piglets(weaned) — Endo-1,3(4)-beta-glucanase: 10 FBG — 
1. In the directions for use of the additive and pre-mixture, indicate the storage temperature, storage life, and stability to pelleting

2. 
Endo-1,3(4)-beta-glucanase: 10-25 FBG

3. For use in compound feed rich in non-starch polysaccharides (mainly beta-glucans), e.g. containing more than 60 % vegetable ingredients (maize, lupin, wheat, barley, soya, oilseed rape or peas)

4. For use in weaned piglets until approximately 35 kg
 Without a time-limit
E 1635 Endo-1,3(4)-beta-glucanaseEC 3.2.1.6 Preparation of endo-1,3(4)-beta-glucanase produced by Trichoderma longibrachiatum (ATCC 2106) having a minimum activity of:
 Liquid form:
Endo-1,3(4)-beta-glucanase: 200 U/ml Chickens for fattening — Endo-1,3(4)-beta-glucanase: 75 U — 
1. In the directions for use of the additive and pre-mixture, indicate the storage temperature, storage life and stability to pelleting

2. Recommended dose per kg of complete feedingstuff: 75-100 U

3. For use in compound feed rich in non-starch polysaccharides (mainly beta-glucans), e.g. containing more than 30 % barley etc.
 Without a time-limit


ANNEX II

EC No or No Additive Chemical formula, description Species or category of animal Maximum age Minimum content Maximum content Other provisions End of period of authorisation
Units of activity/kg of complete feedingstuff
Enzymes
11 Endo-1,4-beta-glucanase EC 3.2.1.4Endo-1,3(4)-beta-glucanase EC 3.2.1.6Endo-1,4-beta-xylanase EC 3.2.1.8 Preparation of endo-1,4-beta-glucanase, endo-1,3(4)-beta-glucanase and endo-1,4-beta-xylanase produced by Trichoderma longibrachiatum (ATCC 74 252) having a minimum activity of:Liquid and granular form:
 Endo-1,4-beta-glucanase: 8 000 U/ml or g
 Endo-1,3(4)-beta-glucanase: 18 000 U/ml or g
 Endo-1,4-beta-xylanase: 26 000 U/ml or g Ducks — Endo-1,4-beta-glucanase: 400 U — 
1. In the directions for use of the additive and pre-mixture, indicate the storage temperature, storage life, and stability to pelleting

2. 

 endo-1,4-beta-glucanase: 400-1 600 U
 endo-1,3(4)-beta-glucanase: 900-3 600 U
 endo-1,4-beta-xylanase: 1 300-5 200 U

3. For use in compound feed rich in non-starch polysaccharides (mainly arabinoxylans and beta-glucans), e.g. containing more than 45 % of either barley and/or triticale
 25.11.2009
Endo-1,3(4)-beta-glucanase: 900 U —
Endo-1,4-beta-xylanase: 1 300 U —
63 Endo-1,4-beta-xylanase EC 3.2.1.8Endo-1,3(4)-beta-glucanase EC 3.2.1.6 Preparation of endo-1,4-beta-xylanase produced by Trichoderma reesei (CBS 529.94) and endo-1,3(4)-beta-glucanase produced by Trichoderma reesei (CBS 526.94) having minimum activities of:Solid form:
 Endo-1,4-beta-xylanase: 800 000 BXU/g
 Endo-1,3(4)-beta-glucanase: 200 000 BU/gLiquid form:
 Endo-1,4-beta-xylanase: 120 000 BXU/ml
 Endo-1,3(4)-beta-glucanase: 30 000 BU/ml Chickens for fattening — Endo-1,4-beta-xylanase: 6 000 BXUEndo-1,3(4)-beta-glucanase: 1 500 BU — 
1. In the directions for use of the additive and pre-mixture, indicate the storage temperature, storage life and stability to pelleting

2. 

 Endo-1,4-beta-xylanase: 16 000-24 000 BXU
 Endo-1,3(4)-beta-glucanase: 4 000-6 000 BU

3. For use in compound feed rich in non-starch polysaccharides (mainly arabinoxylans and glucans), e.g. containing more than 54 % wheat
 25.11.2009
Turkeys for fattening — Endo-1,4-beta-xylanase: 16 000 BXUEndo-1,3(4)-beta-glucanase: 4 000 BU — 
1. In the directions for use of the additive and pre-mixture, indicate the storage temperature, storage life and stability to pelleting

2. 

 Endo-1,4-beta-xylanase: 16 000-40 000 BXU
 Endo-1,3(4)-beta-glucanase: 4 000-10 000 BU

3. For use in compound feed rich in non-starch polysaccharides (mainly arabinoxylans and glucans), e.g. containing more than 44 % wheat
 25.11.2009





ANNEX III

EC No or No Additive Chemical formula, description Species or category of animal Maximum age Minimum content Maximum content Other provisions End of period of authorisation
CFU/kg of complete feedingstuff
Micro-organisms
E 1702 Saccharomyces cerevisiaeNCYC Sc 47 Preparation of Saccharomyces cerevisiae containing a minimum of:5 × 109 CFU/g additive Dairy cows — 4 × 108 2 × 109 In the directions for use of the additive and the pre-mixture, indicate the storage temperature, storage life and stability to pelleting.The quantity of Saccharomyces cerevisiae in the daily ration must not exceed 5,6 × 109 CFU per 100 kg of body weight. Add 8,75 × 109 CFU per each additional 100 kg body weight. Without a time-limit
E 1704 Saccharomyces cerevisiaeCBS 493.94 Preparation of Saccharomyces cerevisiae containing a minimum of:1 × 109 CFU/g additive Dairy cows — 5 × 107 3,5 × 108 In the directions for use of the additive and pre-mixture, indicate the storage temperature, storage life and stability to pelleting.The quantity of Saccharomyces cerevisiae in the daily ration must not exceed 1,2 × 109 CFU for 100 kg of body weight. Add 1,7 × 108 CFU per each additional 100 kg body weight. Without a time-limit