
Article 1 
Annexes I to IV to Regulation (EEC) No 2377/90 are hereby amended as set out in the Annex hereto.
Article 2 
This Regulation shall enter into force on the 60th day following its publication in the Official Journal of the European Communities.
This Regulation shall be binding in its entirety and directly applicable in all Member States.Done at Brussels, 17 July 1998.
For the Commission
Martin BANGEMANN
Member of the Commission
ANNEX


A.. Annex I to Regulation (EEC) No 2377/90 is amended as follows:

1.. Anti-infectious agents

1.1. Chemotherapeutics

1.1.1. Sulfonamides

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘All substances belonging to the sulfonamide group Parent drug All food producing species 100 μg/kg Muscle The combined total residues of all substances within the sulfonamide group should not exceed 100 μg/kg’
100 μg/kg Fat
100 μg/kg Liver
100 μg/kg Kidney
Bovine, ovine, caprine 100 μg/kg Milk
1.1.2. Diamino pyrimidine derivates

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Baquiloprim Baquiloprim Bovine 10 μg/kg Fat 
300 μg/kg Liver
150 μg/kg Kidney
30 μg/kg Milk
Porcine 40 μg/kg Skin + fat
50 μg/kg Liver
50 μg/kg Kidney
Trimethoprim Trimethoprim Bovine 50 μg/kg Muscle 
50 μg/kg Fat
50 μg/kg Liver
50 μg/kg Kidney
50 μg/kg Milk
Porcine 50 μg/kg Muscle
50 μg/kg Skin + fat
50 μg/kg Liver
50 μg/kg Kidney
Equidae 100 μg/kg Muscle
100 μg/kg Fat
100 μg/kg Liver
100 μg/kg Kidney
Poultry not for use in animals from which eggs are produced for human consumption 50 μg/kg Muscle
50 μg/kg Skin + fat
50 μg/kg Liver
50 μg/kg Kidney
Fin fish 50 μg/kg Muscle and skin in natural proportions’
1.2. Antibiotics

1.2.1. Penicillins

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Amoxicyllin Amoxicyllin All food producing species 50 μg/kg Muscle 
50 μg/kg Fat
50 μg/kg Liver
50 μg/kg Kidney
4 μg/kg Milk
Ampicillin Ampicillin All food producing species 50 μg/kg Muscle 
50 μg/kg Fat
50 μg/kg Liver
50 μg/kg Kidney
4 μg/kg Milk
Benzylpenicillin Benzylpenicillin All food producing species 50 μg/kg Muscle 
50 μg/kg Fat
50 μg/kg Liver
50 μg/kg Kidney
4 μg/kg Milk
Cloxacillin Cloxacillin All food producing species 300 μg/kg Muscle 
300 μg/kg Fat
300 μg/kg Liver
300 μg/kg Kidney
30 μg/kg Milk
Oxacillin Oxacillin All food producing species 300 μg/kg Muscle 
300 μg/kg Fat
300 μg/kg Liver
300 μg/kg Kidney
30 μg/kg Milk
Penethamate Benzylpenicillin Bovine 50 μg/kg Muscle 
50 μg/kg Fat
50 μg/kg Liver
50 μg/kg Kidney
4 μg/kg Milk’
1.2.2. Cephalosporins

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Cefazolin Cefazolin Bovine, ovine, caprine 50 μg/kg Milk 
Cefquinome Cefquinome Bovine 50 μg/kg Muscle 
50 μg/kg Fat
100 μg/kg Liver
200 μg/kg Kidney
20 μg/kg Milk’
1.2.3. Quinolones

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Danofloxacine Danofloxacine Bovine (not for use in animals from which milk is produced for human consumption) 200 μg/kg Muscle 
100 μg/kg Fat
400 μg/kg Liver
400 μg/kg Kidney
Chicken (not for use in animals from which eggs are produced for human consumption) 200 μg/kg Muscle
100 μg/kg Skin + fat
400 μg/kg Liver
400 μg/kg Kidney
Difloxacin Difloxacin Chicken, turkey 300 μg/kg Muscle 
400 μg/kg Skin + fat
1 900 μg/kg Liver
600 μg/kg Kidney
Enrofloxacin Sum of enrofloxacin and ciprofloxacin Bovine, porcine, poultry 30 μg/kg Muscle 
30 μg/kg Liver
30 μg/kg Kidney
Sarafloxacin Sarafloxacin Chicken 10 μg/kg Skin + fat 
100 μg/kg Liver’
1.2.4. Macrolides

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Spiramycin Sum of spiramycin and neospiramycin Bovine 200 μg/kg Muscle 
300 μg/kg Fat
300 μg/kg Liver
300 μg/kg Kidley
200 μg/kg Milk
Chicken 200 μg/kg Muscle
300 μg/kg Skin + fat
400 μg/kg Liver
Tilmicosin Tilmicosin Bovine, ovine, porcine 1 000 μg/kg Liver 
1 000 μg/kg Kidney
Ovine 50 μg/kg Milk
Tylosin Tylosin A Bovine 100 μg/kg Muscle 
100 μg/kg Fat
100 μg/kg Liver
100 μg/kg Kidney
50 μg/kg Milk
Porcine 100 μg/kg Muscle
100 μg/kg Skin + fat
100 μg/kg Liver
100 μg/kg Kidney
Poultry (not for use in hens producing eggs for human consumption) 100 μg/kg Muscle
100 μg/kg Skin + fat
100 μg/kg Liver
 100 μg/kg Kidney’
1.2.5. Florfenicol and related compounds

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Florfenicol Sum of florfenicol and its metabolites measured as florfenicol-amine Bovine 200 μg/kg Muscle 
3 000 μg/kg Liver
300 μg/kg Kidney’
1.2.6. Tetracyclines

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Chlortetracycline Sum of parent drug and its 4-epimer All food producing species 100 μg/kg Muscle 
300 μg/kg Liver
600 μg/kg Kidney
100 μg/kg Milk
200 μg/kg Eggs
Doxycycline Doxycycline Bovine 100 μg/kg Muscle 
300 μg/kg Liver
600 μg/kg Kidney
Porcine, poultry 100 μg/kg Muscle
300 μg/kg Skin + fat
300 μg/kg Liver
600 μg/kg Kidney
Oxytetracycline Sum of parent drug and its 4-epimer All food producing species 100 μg/kg Muscle 
300 μg/kg Liver
600 μg/kg Kidney
100 μg/kg Milk
200 μg/kg Eggs
Tetracycline Sum of parent drug and its 4-epimer All food producing species 100 μg/kg Muscle 
300 μg/kg Liver
600 μg/kg Kidney
100 μg/kg Milk
200 μg/kg Eggs’
1.2.7. Thiamphenicol and related compounds

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Thiamphenicol Thiamphenicol Bovine 50 μg/kg Muscle 
50 μg/kg Fat
50 μg/kg Liver
50 μg/kg Kidney
50 μg/kg Milk
Chicken (not for use in animals from which eggs are produced for human consumption) 50 μg/kg Muscle
50 μg/kg Skin + fat
50 μg/kg Liver
50 μg/kg Kidney’
2.. Antiparasitic agents

2.1. Agents acting against endoparasites

2.1.1. Salicylanilides

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Closantel Closantel Bovine 1 000 μg/kg Muscle 
3 000 μg/kg Fat
1 000 μg/kg Liver
3 000 μg/kg Kidney
Ovine 1 500 μg/kg Muscle
2 000 μg/kg Fat
1 500 μg/kg Liver
5 000 μg/kg Kidney’
2.1.2. Tatra-hydro-imidazoles (imidazolthiazoles)

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Levamisole Levamisole Bovine, ovine, porcine, poultry 10 μg/kg Muscle 
10 μg/kg Fat
100 μg/kg Liver
10 μg/kg Kidney’
2.1.3. Benzimidazoles and pro-benzimidazoles

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Febantel Sum of extractable residues which may be oxidised to oxfendazole sulphone Bovine, ovine 10 μg/kg Milk 
Bovine, ovine, porcine, equidae 50 μg/kg Muscle
50 μg/kg Fat
500 μg/kg Liver
50 μg/kg Kidney
Fenbendazole Sum of extractable residues which may be oxidised to oxfendazole sulphone Bovine, ovine 10 μg/kg Milk 
Bovine, ovine, porcine, equidae 50 μg/kg Muscle
50 μg/kg Fat
500 μg/kg Liver
50 μg/kg Kidney
Flubendazole Sum of flubendazole and (2-amino 1H-benzimidazol-5-yl) (4-flurorophenyl)methanone Porcine, chicken, game birds 50 μg/kg Muscle 
50 μg/kg Skin + fat
400 μg/kg Liver
300 μg/kg Kidney
Flubendazole Chicken 400 μg/kg Eggs
Oxfendazole Sum of extractable residues which may be oxidised to oxfendazole sulphone Bovine, ovine 10 μg/kg Milk 
Bovine, ovine, porcine, equidae 50 μg/kg Muscle
50 μg/kg Fat
500 μg/kg Liver
50 μg/kg Kidney
Oxibendazole Oxibendazole Porcine 100 μg/kg Muscle 
500 μg/kg Skin + fat
200 μg/kg Liver
100 μg/kg Kidney
Thiabendazole Sum of thiabendazole and 5-hydroxythiabendazole Bovine 100 μg/kg Muscle 
100 μg/kg Fat
100 μg/kg Liver
100 μg/kg Kidney
100 μg/kg Milk
Triclabendazole Sum of extractable residues that may be oxidised to ketotriclaben-dazole Bovine, ovine 100 μg/kg Muscle Not for use in animals from which milk is produced for human consumption’
100 μg/kg Liver
100 μg/kg Kidney
2.2. Agents acting against ectoparasites

2.2.1. Organophosphates

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Diazinon Diazinon Bovine, ovine, caprine 20 μg/kg Milk 
Bovine, porcine, ovine, caprine 20 μg/kg Muscle
700 μg/kg Fat
20 μg/kg Liver
20 μg/kg Kidney’
2.2.2. Formamidines

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Amitraz Sum of amitraz and all metabolites containing the 2,4-DMA moeity, expressed as amitraz Porcine 400 μg/kg Skin + fat 
200 μg/kg Liver
200 μg/kg Kidney’
2.3. Agents acting against endo- and ectoparasites

2.3.1. Avermectins

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Abamectin Avermectin Bla Bovine 10 μg/kg Fat 
20 μg/kg Liver
Doramectin Doramectin Bovine 10 μg/kg Muscle Not for use in ovines from which milk is produced for human consumption’
150 μg/kg Fat
100 μg/kg Liver
30 μg/kg Kidney
Porcine, ovine 20 μg/kg Muscle
100 μg/kg Fat
50 μg/kg Liver
30 μg/kg Kidney
Eprinomectin Eprinomectin Bla Bovine 30 μg/kg Muscle 
30 μg/kg Fat
600 μg/kg Liver
100 μg/kg Kidney
30 μg/kg Milk
Ivermectin 22,23-Dihydro-aver-mectin Bla Bovine 40 μg/kg Fat 
100 μg/kg Liver
Porcine, ovine, equidae 20 μg/kg Fat
15 μg/kg Liver
Moxidectin Moxidectin Bovine, ovine 50 μg/kg Muscle 
500 μg/kg Fat
100 μg/kg Liver
50 μg/kg Kidney
3.. Agents acting on the nervous system

3.2. Agents acting on the autonomic nervous system

3.2.1. Anti-adrenergics

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Carazolol Carazolol Porcine 5 μg/kg Muscle 
5 μg/kg Skin + fat
25 μg/kg Liver
25 μg/kg Kidney’
4.. Anti-infammatory agents

4.1. Nonsteroidal anti-infammatory agents

4.1.1. Arylpropionic acid derivative

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Vedaprofen Vedaprofen Equidae 50 μg/kg Muscle 
20 μg/kg Fat
100 μg/kg Liver
1 000 μg/kg Kidney’
4.1.2. Fenamate group derivates

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Tolfenamic acid Tolfenamic acid Bovine 50 μg/kg Muscle 
400 μg/kg Liver
100 μg/kg Kidney
50 μg/kg Milk
Porcine 50 μg/kg Muscle
400 μg/kg Liver
100 μg/kg Kidney’
5.. Corticoides

5.1. Glucocorticoides

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Dexamethasone Dexamethasone Bovine 03 μg/kg Milk 
Bovine, porcine, equidae 0,75 μg/kg Muscle
2 μg/kg Liver
0,75 μg/kg Kidney’
B.. Annexe II to Regulation (EEC) No 2377/90 is amended as follows:

1.. Inorganic chemicals

Pharmacologically active substance(s) Animal species Other provisions
‘Bismuth subcarbonate All food producing species For oral use only
Bismuth subgallate All food producing species For oral use only
Bismuth subnitrate All food producing species For oral use only
Bismuth subsalicylate All food producing species For oral use only
Boric acid and borates All food producing species 
Bromide, Sodium salt All mammalian food producing species For topical use only
Calcium acetateAll food producing speciesCalcium benzoateCalcium carbonateCalcium chlorideCalcium gluconateCalcium hydroxideCalcium hypophosphiteCalcium malateCalcium oxideCalcium phosphateCalcium polyphosphatesCalcium propionateCalcium silicateCalcium stearate Calcium sulphate 
Hydrochloric acid All food producing species For use as excipient
Hydrogen peroxide All food producing species 
Iodine and iodine inorganic compounds including:
— All food producing species
— Sodium and potassium-iodide
— Sodium and potassium-iodide Iodophors including polyvinylpyrrolidone-iodine 
MagnesiumAll food producing speciesMagnesium sulphateMagnesium hydroxideMagnesium stearateMagnesium glutamateMagnesium orotateMagnesium aluminium silicateMagnesium oxideMagnesium carbonateMagnesium phosphateMagnesium glycerophosphateMagnesium asparateMagnesium citrateMagnesium acetate Magnesium trisilicate 
Potassium DL-aspartate All food producing species 
Potassium glucuronate All food producing species 
Potassium glycerophosphate All food producing species 
Potassium nitrate All food producing species 
Potassium selenate All food producing species 
Sodium chlorite Bovine For topical use only
Sodium dichloroisocyanurate Bovine, ovine, caprine For topical use only’
Sodium selenate All food producing species 
Sodium selenite All food producing species 
Sulphur Bovine, porcine, ovine, caprine, equidae 
Zinc acetateAll food producing speciesZinc chlorideZinc gluconateZinc oleate Zinc stearate 
2.. Organic compounds

Pharmacologically active substance(s) Animal species Other provisions
‘17B-Oestradiol All mammalian food producing species For therapeutic and zootechnical uses only
Acetyl cysteine All food producing species 
Alfaprostol Bovine, porcine, equidae 
Benzylalcohol All food producing species For use as excipient
Betaine All food producing species 
Brotizolam Bovine For therapeutic uses only
Buserelin All food producing species 
Butyl 4-hydroxybenzoate All food producing species 
Caffeine All food producing species 
Carbetocin All mammalian food producing species 
Cefazolin BovineOvine, caprine For intramammary use (except if the udder may be used as food for human consumption)
Cetrimide All food producing species 
Chlorhexidine All food producing species For topical use only
Chlorocresol All food producing species 
Cloprostenol Bovine, porcine, equidae 
D-phe 6-luteinizing-hormone-releasing-hormone All food producing species 
Dembrexine Equidae 
Detomidine Bovine, equidae For therapeutic uses only
Diclazuril Ovine For oral use in lambs only
Dicloxacillin All food producing species 
Diethyl phtalate All food producing species 
Dimethyl phtalate All food producing species 
Dinoprost tromethamine All mammalian food producing species 
Etamiphylline camsylate All food producing species 
Ethanol All food producing species For use as excipient
Ethyl lactate All food producing species 
Etiproston tromethamine Bovine, porcine 
Fertirelin acetate Bovine 
Folic acid All food producing species 
Glycerol formal All food producing species 
Gonadotrophin releasing hormone All food producing species 
Heptaminol All food producing species 
Hesperidin Equidae 
Hesperidin methyl chalcone Equidae 
Human chorion gonadotrophin (HCG) All food producing species 
Human menopausal urinary gonadotrophin Bovine 
Iodine organic compounds:
— Iodoform All food producing species 
Isobutane All food producing species 
Isoflurane Equidae For use as anaesthetic only
Isoxsuprine Bovine, equidae For therapeutic use only in accordance with Council Directive 96/22/EEC (OJ L 125, 23.5.1996, p. 3)
Ketanserin tartrate Equidae 
Ketoprofen Bovine, equidaePorcine 
L-tartaric acid and its mono- and di- basic salt of sodium, potassium and calcium All food producing species For use as excipient
Lactic acid All food producing species 
Lecirelin  
Lini oleum All food producing species 
Lobeline All food producing species 
Luprostiol All mammalian species 
Malic acid All food producing species For use as excipient
Medroxyprogesterone acetate Ovine For intravaginal use for zootechnical purposes only
Melatonin Ovine, caprine 
Menbutone Bovine, ovine, caprine, porcine, equidae 
Menthol All food producing species 
Mineral hydrocarbons, low to high viscosity including micro-cristalline waxes, approximately C10-C60; aliphatic, branched aliphatic and alicyclic compounds All food producing species Excludes aromatic and unsaturated compounds
N-butane All food producing species 
N-butanol All food producing species For use as excipient
Neostigmine All food producing species 
Oxytocin All mammalian food producing species 
Pancreatin All mammalian food producing species For topical use only
Papain All food producing species 
Papaverine Bovine New-born calves only
Peracetic acid All food producing species 
Phenol All food producing species 
Phloroglucinol All food producing species 
Policresulene All food producing species For topical use only
Polysulphated glycosaminoglycan Equidae 
Praziquantel Ovine For non-lactating sheep only
Pregnant mare serum gonadotrophin All food producing species 
Propane All food producing species 
Propylene glycol All food producing species 
Quatresin All food producing species For use as preservative only at concentrations of up to 0,5 %
Quillaia saponins All food producing species 
R-clopostenol Bovine, porcine, equidae 
Rifaximin Bovine For intramammary use - except if the udder may be used as food for human consumption - and intra-uterine use only
Romifidine Equidae For therapeutic uses only
Sodium benzyl 4-hydroxybenzoate All food producing species 
Sodium butyl 4-hydroxybenzoate All food producing species 
Somatosalm Salmon 
Tau fluvalinate Honey bees 
Theobromine All food producing species 
Theophylline All food producing species 
Thiomersal All food producing species For use only as preservatives in multi-dose vaccines at a concentration not exceeding 0,02 %
Thymol All food producing species 
Timerfonate All food producing species For use only as preservatives in multi-dose vaccines at a concentration not exceeding 0,02 %’
Trimethylphloroglucinol All food producing species 
3.. Substances generally recognised as safe

Pharmacologically active substance(s) Animal species Other provisions
‘Absinthium extract All food producing species 
Acetylmethionine All food producing species 
Aluminium hydroxide All food producing species 
Aluminium monostearate All food producing species 
Ammonium sulfate All food producing species 
Benzoyl benzoate All food producing species 
Benzyl p-hydroxybenzoate All food producing species 
Calcium borogluconate All food producing species 
Calcium citrate All food producing species 
Camphor All food producing species External use only’
Cardamon extract All food producing species 
Diethyl sebacate All food producing species 
Dimethicone All food producing species 
Dimethyl acetamide All food producing species 
Dimethyl sulphoxide All food producing species 
Epinephrine All food producing species 
Ethyl oleate All food producing species 
Ethylenediaminetetraacetic acid and salts All food producing species 
Eucalyptol All food producing species 
Follicle stimulating hormone (natural FSH from all species and their synthetic analogues) All food producing species 
Formaldehyde All food producing species 
Formic acid All food producing species 
Glutaraldehyde All food producing species 
Guaiacol All food producing species 
Heparin and its salts All food producing species 
Human chorionic gonadotropin (natural HCG and its synthetic analogues) All food producing species 
Iron ammonium citrate All food producing species 
Iron dextran All food producing species 
Iron glucoheptonate All food producing species 
Isopropanol All food producing species 
Luteinising hormone (natural LH from all species and their synthetic analogues) All food producing species 
Lanolin All food producing species 
Magnesium chloride All food producing species 
Magnesium gluconate All food producing species 
Magnesium hypophosphite All food producing species 
Mannitol All food producing species 
Methylbenzoate All food producing species 
Monothioglycerol All food producing species 
Montanide All food producing species 
Myglyol All food producing species 
Orgotein All food producing species 
Poloxalene All food producing species 
Poloxamer All food producing species 
Polyethylene glycols (molecular weight ranging from 200 to 10 000) All food producing species 
Polysorbate 80 All food producing species 
Serotonin All food producing species 
Sodium chloride All food producing species 
Sodium cromoglycate All food producing species 
Sodium dioctylsulphosuccinate All food producing species 
Sodium formaldehydesulphoxylate All food producing species 
Sodium lauryl sulphate All food producing species 
Sodium pyrosulphite All food producing species 
Sodium stearate All food producing species 
Sodium thiosulphate All food producing species 
Tragacanth All food producing species 
Urea All food producing species 
Zinc oxide All food producing species 
Zinc sulphate All food producing species 
4.. Substances used in homeopathic veterinary medicinal products

Pharmacologically active substance(s) Animal species Other provisions
‘All substances used in homeopathic veterinary medicinal products provided that their concentration in the product does not exceed one part per 10 000 All food producing species’ 
5.. Substances used as food additives in foodstuffs for human consumption

Pharmacologically active substance(s) Animal species Other provisions
‘Substances with an E number All food producing species Only substances approved as additives in foodstuffs for human consumption, with the exception of preservatives listed in Part C of Annex III to European Parliament and Council Directive 95/2/EC (OJ L 61, 18. 3. 1995, p. 1.)’
C.. Annex III to Regulation (EEC) No 2377/90 is amended as follows:

1.. Anti-infectious agents

1.1. Chemotherapeutics

1.1.2. Benzenesulphonamides

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Clorsulon Clorsulon Bovine 50 μg/kg Muscle Provisional MRLs expire on 1 January 2000’
150 μg/kg Liver
400 μg/kg Kidney
1.2. Antibiotics

1.2.1. Beta-lactamase inhibitors

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Clavulanic acid Clavulanic acid Bovine, ovine 200 μg/kg Milk Provisional MRLs expire on 1 July 1999’
Bovine, ovine, porcine 200 μg/kg Muscle
200 μg/kg Fat
200 μg/kg Liver
200 μg/kg Kidney
1.2.2. Macrolides

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Erythromycin Erythromycin Bovine, ovine 40 μg/kg Milk Provisional MRLs expire on 1 June 2000; MRLs apply to all microbiological active residues expressed as erythromycin equivalent
Bovine, ovine, porcine, poultry 400 μg/kg Muscle
400 μg/kg Fat
400 μg/kg Liver
400 μg/kg Kidney
Poultry 200 μg/kg Eggs
Josamycin Josamycin Chicken 200 μg/kg Muscle Provisional MRLs expire on 1 July 2000’
200 μg/kg Fat
200 μg/kg Liver
400 μg/kg Kidney
200 μg/kg Eggs
1.2.4. Cephalosporins

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Ceftiofur Sum of all residues retaining the betalactam structure expressed as desfuroylceftiofur Bovine 200 μg/kg Muscle Provisional MRLs expire on 1 January 1999
600 μg/kg Fat
2 000 μg/kg Liver
2 000 μg/kg Kidney
100 μg/kg Milk
Porcine 500 μg/kg Muscle
600 μg/kg Fat
3 000 μg/kg Liver
4 000 μg/kg Kidney
Cephapirin Sum of cephapirin and desacetylcephapirin Bovine 50 μg/kg 50 μg/kg Muscle
Fat Provisional MRLs expire on 1 January 1999’
50 μg/kg Liver
100 μg/kg Kidney
10 μg/kg Milk
1.2.5. Aminoglycosides

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Aminosidine Aminosidine Bovine, porcine, rabbits, chicken 500 μg/kg Muscle Provisional MRLs expire on 1 July 2000
1 500 μg/kg Liver
1 500 μg/kg kidney
Apramycin Apramycin Bovine (for use in non-lactating cattle only) 1 000 μg/kg Muscle Provisional MRLs expire on 1 July 1999
1 000 μg/kg Liver
10 000 μg/kg Liver
20 000 μg/kg Kidney
Porcine 1 000 μg/kg Muscle
1 000 μg/kg Skin and fat
1 000 μg/kg Liver
5 000 μg/kg Kidney
Dihydrostreptomycin Dihydrostreptomycin Bovine, ovine 200 μg/kg Milk Provisional MRLs expire on 1 June 2000
Bovine, ovine, porcine, poultry 500 μg/kg Muscle
500 μg/kg Fat
500 μg/kg Liver
1 000 μg/kg Kidney
Gentamicin Gentamicin Bovine 100 μg/kg Milk Provisional MRLs expire on 1 June 2000
Bovine, porcine 100 μg/kg Muscle
100 μg/kg Fat
200 μg/kg Liver
1 000 μg/kg Kidney
Neomycin (including Neomycin Bovine, ovine, caprine 500 μg/kg Milk Provisional MRLs expire on 1 June 2000 framycetin)
Bovine, ovine, caprine, porcine, chicken, 500 μg/kg Muscle turkey, duck
500 μg/kg Fat
500 μg/kg Liver
5 000 μg/kg Kidney
Chicken 500 μg/kg Eggs
Spectinomycin Spectinomycin Bovine 200 μg/kg Milk Provisional MRLs expire on 1 July 1998
Bovine, porcine, poultry 300 μg/kg Muscle
500 μg/kg Fat
2 000 μg/kg Liver
5 000 μg/kg Kidney
Streptomycin Streptomycin Bovine, ovine 200 μg/kg Milk Provisional MRLs expire on 1 June 2000’
Bovine, ovine, porcine, poultry 500 μg/kg Muscle
500 μg/kg Fat
500 μg/kg Liver
1 000 μg/kg Kidney
1.2.6. Quinolones

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Decoquinate Decoquinate Bovine, ovine 500 μg/kg Muscle Provisional MRLs expire on 1 July 2000
500 μg/kg Fat
500 μg/kg Liver
500 μg/kg Kidney
Flumequine Flumequine Bovine, ovine, porcine, chicken 50 μg/kg Muscle Provisional MRLs expire on 1 January 2000
Flumequine Flumequine Bovine, ovine, porcine, chicken 50 μg/kg Fat or skin + fat Provisional MRLs expire on 1 January 2000
100 μg/kg Liver
300 μg/kg Kidney
Salmonidae 150 μg/kg 
Marbofloxacin Marbofloxacin Bovine 150 μg/kg Muscle Provisional MRLs expire on 1 July 2000
50 μg/kg Fat
150 μg/kg Liver
150 μg/kg Kidney
75 μg/kg Milk
Porcine 150 μg/kg Muscle
50 μg/kg Skin + fat
150 μg/kg Liver
150 μg/kg Kidney
Sarafloxacin Sarafloxacin Salmonidae 30 μg/kg Muscle and skin in natural proportions Provisional MRLs expire on 1 July 1998’
1.2.9. Polymyxins

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Colistin Colistin Bovine, ovine 50 μg/kg Milk Provisional MRLs expire on 1 July 2000’
Bovine, ovine, porcine, chicken, rabbits 150 μg/kg Muscle
150 μg/kg Fat
150 μg/kg Liver
200 μg/kg Kidney
Chicken 300 μg/kg Eggs
1.2.10. Penicillins

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Nafcillin Nafcillin Bovine 30 μg/kg Muscle Provisional MRLs expire on 1 January 1999For intramammary use only
30 μg/kg Fat
30 μg/kg Liver
30 μg/kg Kidney
30 μg/kg Milk
Penethamate Benzylpenicillin Ovine 150 μg/kg Muscle Provisional MRLs expire on 1 January 2000’
150 μg/kg Fat
150 μg/kg Liver
150 μg/kg Kidney
4 μg/kg Milk
Porcine 50 μg/kg Muscle
50 μg/kg Fat
50 μg/kg Liver
50 μg/kg Kidney
1.2.11. Florfenicol and related compounds

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Florfenicol Sum of florfenicol and its metabolites measured as florfenicol-amine Fish 1 000 μg/kg Muscle and skin in natural proportions Provisional MRLs expire on 1 July 2001’
2.. Antiparasitic agents

2.1. Agents acting against endoparasites

2.1.2. Benzimidazoles and pro-benzimidazoles

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Albendazole sulphoxide Sum of albendazole, albendazole sulphoxide, albendazole sulphone, and albendazole 2-amino sulphone, expressed as albendazole Bovine, ovine 100 μg/kg Milk Provisional MRLs expire on 1 January 2000
Bovine, ovine, pheasant 100 μg/kg Muscle
100 μg/kg Fat
1 000 μg/kg Liver
500 μg/kg Kidney
Netobimin Sum of netobimin and albendazole and metabolites of albendazole measured as 2-amino-benzimidazole sulphone Bovine, ovine, caprine 100 μg/kg Muscle Provisional MRLs expire on 31 July 1999’
100 μg/kg Fat
1 000 μg/kg Liver
500 μg/kg Kidney
100 μg/kg Milk
2.2. Agents acting against ectoparasites

2.2.1. Formamidines

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Amitraz Sum of amitraz and metabolites which are measured as 2,4-dime-thylaniline Bovine 200 μg/kg Fat Provisional MRLs expire on 1 July 1998
200 μg/kg Liver
200 μg/kg Kidney
10 μg/kg Milk
Ovine 400 μg/kg Fat
200 μg/kg Liver
200 μg/kg Kidney
Sum of amitraz and all metabolites containing the 2,4-DMA moeity, expressed as amitraz Bees 200 μg/kg Honey Provisional MRLs expire on 1 July 1999’
2.2.2. Iminophenyl thiazolidine derivative

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Cymiazole Cymiazole Bees 1 000 μg/kg Honey Provisional MRLs expire on 1 July 1999’
2.2.4. Organophosphates

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Azamethiphos Azamethiphos Salmonidae 100 μg/kg Muscle and skin in natural proportions Provisional MRLs expire on 1 June 1999’
2.2.5. Acyl urea derivates

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Teflubenzuron Teflubenzuron Salmonidae 500 μg/kg Muscle And skin in natural proportions Provisional MRLs expire on 1 July 1999’
2.3. Agents acting against endo- and ectoparasites

2.3.1. Avermectins

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Ivermectin 22,23-Dihydro-aver-mectin Bla Deer, including reindeer 20 μg/kg Muscle Provisional MRLs expire on 1 January 1999
100 μg/kg Fat
50 μg/kg Liver
20 μg/kg Kidney
Moxidectin Moxidectin Equidae 50 μg/kg Muscle Provisional MRLs expire on 1 January 2000’
500 μg/kg Fat
100 μg/kg Liver
50 μg/kg Kidney
3.. Agents acting on the nervous system

3.2. Agents acting on the autonomic nervous system

3.2.1. 62 sympathomimetic agents

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Clenbuterol hydrochloride Clenbuterol Bovine (indication: solely for tocolysis in parturient cows) 0,1 μg/kg Muscle Provisional MRLs expire on 1 July 2000’
0,5 μg/kg Liver
0,5 μg/kg Kidney
0,05 μg/kg Milk
Equidae (indications: locolysis and the treatment of respiratory ailments) 0,1 μg/kg Muscle
0,5 μg/kg Liver
0,5 μg/kg Kidney
5.. Anti-inflammatory agents

5.1. Non-steroidal anti-inflammatory agents

5.1.1. Arylpropionic acid derivative

Pharmacologically active substance(s) Marker residue Animal species MRLs Target tissues Other provisions
‘Carprofen Carprofen Bovine 500 μg/kg Muscle Provisional MRLs expire on 1 January 2000’
500 μg/kg Fat
1 000 μg/kg Liver
1 000 μg/kg Kidney
Equidae 50 μg/kg Muscle
100 μg/kg Fat
1 000 μg/kg Liver
1 000 μg/kg Kidney
D.. Annex IV to Regulation (EEC) No 2377/90 is amended as follows:

Pharmacologically active substance(s)
‘Chloramphenicol
Chloroform
Chlorpromazine
Colchicine
Dapsone
Dimetridazole
Furazolidone
Metronidazole
Nitrofurans
Ronidazole’
